Effect of Endomorphin-1 on Contractile Activity of Rat Mesenteric Lymphatic Vessels


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We studied the effect of endomorphin-1 on isolated mesenteric lymphatic vessels in rats. It was found that endomorphin-1 caused a dose-dependent increase in the contractile activity of lymphangions, which was associated with stimulation of intracellular calcium depots. The observed effect of endomorphin-1 in isolated lymphatic vessels has a complex mechanism; it depends on the concentration of the applied peptide and is probably determined by its interaction with non-opioid receptors

Sobre autores

O. Nechaykina

Research Institute of Hygiene, Occupational Pathology, and Human Ecology, Federal Medical-Biological Agency of Russia

Autor responsável pela correspondência
Email: olga2278@mail.ru
Rússia, Kuzmolovsky, Leningrad Region

S. Petunov

Research Institute of Hygiene, Occupational Pathology, and Human Ecology, Federal Medical-Biological Agency of Russia

Email: olga2278@mail.ru
Rússia, Kuzmolovsky, Leningrad Region

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