Email this article Development of a Bacteriophage Complex with Superhydrophilic and Superhydrophobic Nanotextured Surfaces of Metals Preventing Healthcare-Associated Infections (HAI)
- Authors: Kaminskii V.V.1, Aleshkin A.V.1, Zul’karneev E.R.1, Zatevalov A.M.1, Kiseleva I.A.1, Efimova O.G.1, Emelyanenko K.A.2, Emelyanenko A.M.2, Boinovich L.B.2
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Affiliations:
- G. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
- A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Science
- Issue: Vol 167, No 4 (2019)
- Pages: 500-503
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241827
- DOI: https://doi.org/10.1007/s10517-019-04559-0
- ID: 241827
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Abstract
We studied antibacterial properties of organo-inorganic hybrid coatings on the AMg2 aluminum alloy including superhydrophilic and superhydrophobic nanotextured metal substrates with applied bacteriophage particles. Bactericidal activity of surfaces after artificial contamination with a bacterial suspension was evaluated. To increase bactericidal effect of the plates, bacteriophage was sorbed on their surface. In the experiments simulating possible spreading of HAI pathogens, higher bactericidal activity of superhydrophilic surfaces in comparison with superhydrophobic ones. Application of bacteriophage particles did not prevent primary colonization of textured metal surfaces by strains used in the experiment, but in some cases increases their bactericidal activity.
About the authors
V. V. Kaminskii
G. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: andreialeshkin@gmail.com
Russian Federation, Moscow
A. V. Aleshkin
G. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Author for correspondence.
Email: andreialeshkin@gmail.com
Russian Federation, Moscow
E. R. Zul’karneev
G. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: andreialeshkin@gmail.com
Russian Federation, Moscow
A. M. Zatevalov
G. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: andreialeshkin@gmail.com
Russian Federation, Moscow
I. A. Kiseleva
G. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: andreialeshkin@gmail.com
Russian Federation, Moscow
O. G. Efimova
G. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Email: andreialeshkin@gmail.com
Russian Federation, Moscow
K. A. Emelyanenko
A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Science
Email: andreialeshkin@gmail.com
Russian Federation, Moscow
A. M. Emelyanenko
A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Science
Email: andreialeshkin@gmail.com
Russian Federation, Moscow
L. B. Boinovich
A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Science
Email: andreialeshkin@gmail.com
Russian Federation, Moscow
