Correction of Acute Parodontitis with Indolicidin Analogues
- Authors: Kutepov I.V.1, Lyashev Y.D.1, Artyushkova E.B.1, Solin A.V.1, Serikov V.S.1, Lyashev A.Y.1, Chahine A.R.2
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Affiliations:
- Department of pathophysiology, Kursk State Medical University
- ABC Medical Imaging, ABC Laboratories
- Issue: Vol 167, No 1 (2019)
- Pages: 47-49
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241435
- DOI: https://doi.org/10.1007/s10517-019-04457-5
- ID: 241435
Cite item
Abstract
We studied the influence of synthetic indolicidin analogues on the development of acute periodontitis. The corrective effect was found in indolicidin analogues Nos. 7 and 8; it manifested in a decrease in the edema of gingival epithelium and lamina propria, a decrease in the relative area of inflammatory infiltrates, and a significant increase in the relative area of normal connective tissue. These changes were revealed as soon as on day 14 and were most pronounced in 21 days after the removal of the ligature. Indolicidin analogues Nos. 7 and 8 demonstrated similar effectiveness on the model of acute periodontitis.
About the authors
I. V. Kutepov
Department of pathophysiology, Kursk State Medical University
Author for correspondence.
Email: medps@yandex.ru
Russian Federation, Kursk
Yu. D. Lyashev
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Russian Federation, Kursk
E. B. Artyushkova
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Russian Federation, Kursk
A. V. Solin
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Russian Federation, Kursk
V. S. Serikov
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Russian Federation, Kursk
A. Yu. Lyashev
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Russian Federation, Kursk
A. R. Chahine
ABC Medical Imaging, ABC Laboratories
Email: medps@yandex.ru
Lebanon, Beirut
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