Correction of Acute Parodontitis with Indolicidin Analogues
- Авторы: Kutepov I.1, Lyashev Y.1, Artyushkova E.1, Solin A.1, Serikov V.1, Lyashev A.1, Chahine A.2
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Учреждения:
- Department of pathophysiology, Kursk State Medical University
- ABC Medical Imaging, ABC Laboratories
- Выпуск: Том 167, № 1 (2019)
- Страницы: 47-49
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241435
- DOI: https://doi.org/10.1007/s10517-019-04457-5
- ID: 241435
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Аннотация
We studied the influence of synthetic indolicidin analogues on the development of acute periodontitis. The corrective effect was found in indolicidin analogues Nos. 7 and 8; it manifested in a decrease in the edema of gingival epithelium and lamina propria, a decrease in the relative area of inflammatory infiltrates, and a significant increase in the relative area of normal connective tissue. These changes were revealed as soon as on day 14 and were most pronounced in 21 days after the removal of the ligature. Indolicidin analogues Nos. 7 and 8 demonstrated similar effectiveness on the model of acute periodontitis.
Об авторах
I. Kutepov
Department of pathophysiology, Kursk State Medical University
Автор, ответственный за переписку.
Email: medps@yandex.ru
Россия, Kursk
Yu. Lyashev
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Россия, Kursk
E. Artyushkova
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Россия, Kursk
A. Solin
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Россия, Kursk
V. Serikov
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Россия, Kursk
A. Lyashev
Department of pathophysiology, Kursk State Medical University
Email: medps@yandex.ru
Россия, Kursk
A. Chahine
ABC Medical Imaging, ABC Laboratories
Email: medps@yandex.ru
Ливан, Beirut