Email this article Specific Features of Gastroesophageal Reflux Disease in Patients with Overweight (Basis for Personalized Treatment)
- Authors: Kseneva S.I.1, Borodulina E.V.1, Selivanova N.E.1, Mareev I.V.1, Udut V.V.1,2
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Affiliations:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
- National Research Tomsk State University
- Issue: Vol 165, No 2 (2018)
- Pages: 213-215
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240171
- DOI: https://doi.org/10.1007/s10517-018-4132-8
- ID: 240171
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Abstract
А cross-sectional study was performed on a continuous sample of patients (N=52) with the gastroesophageal reflux disease. Specific features of this disease in patients with overweight were revealed. Regurgitation predominated in the structure of complaints. Fibrogastroduodenoscopy revealed endoscopically negative form of the diseases in 38% of cases. According to 24-h pH monitoring results, alkaline reflux pH>7 took more than 25% time in supine position at high DeMeester score, which limits the usage of aggressive acid-lowering therapy.
About the authors
S. I. Kseneva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Author for correspondence.
Email: viksbest@mail.ru
Russian Federation, Moscow
E. V. Borodulina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: viksbest@mail.ru
Russian Federation, Moscow
N. E. Selivanova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: viksbest@mail.ru
Russian Federation, Moscow
I. V. Mareev
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: viksbest@mail.ru
Russian Federation, Moscow
V. V. Udut
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences; National Research Tomsk State University
Email: viksbest@mail.ru
Russian Federation, Moscow; Tomsk
