Specific Features of Gastroesophageal Reflux Disease in Patients with Overweight (Basis for Personalized Treatment)
- Авторы: Kseneva S.1, Borodulina E.1, Selivanova N.1, Mareev I.1, Udut V.1,2
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Учреждения:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
- National Research Tomsk State University
- Выпуск: Том 165, № 2 (2018)
- Страницы: 213-215
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240171
- DOI: https://doi.org/10.1007/s10517-018-4132-8
- ID: 240171
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Аннотация
А cross-sectional study was performed on a continuous sample of patients (N=52) with the gastroesophageal reflux disease. Specific features of this disease in patients with overweight were revealed. Regurgitation predominated in the structure of complaints. Fibrogastroduodenoscopy revealed endoscopically negative form of the diseases in 38% of cases. According to 24-h pH monitoring results, alkaline reflux pH>7 took more than 25% time in supine position at high DeMeester score, which limits the usage of aggressive acid-lowering therapy.
Об авторах
S. Kseneva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: viksbest@mail.ru
Россия, Moscow
E. Borodulina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: viksbest@mail.ru
Россия, Moscow
N. Selivanova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: viksbest@mail.ru
Россия, Moscow
I. Mareev
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: viksbest@mail.ru
Россия, Moscow
V. Udut
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences; National Research Tomsk State University
Email: viksbest@mail.ru
Россия, Moscow; Tomsk