Potentialities of MicroRNA Diagnosis in Patients with Bladder Cancer


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Abstract

Despite promising vista of the use of microRNA in molecular diagnosis of bladder cancer, there are few data on their expression profiles, which impedes assessment of diagnostic value of these marker molecules. In this study, suppression subtractive hybridization, on-chip hybridization, and high-throughput deep sequencing focused on profiling microRNA and assessing the diagnostic value of revealed marker molecules.

About the authors

P. V. Shegay

National Medical Radiological Research Center, Ministry of Health of the Russian Federation

Author for correspondence.
Email: dr.shegay@mail.ru
Russian Federation, Moscow

A. A. Zhavoronkov

First Oncology Research and Advisory Center (FORAC)

Email: dr.shegay@mail.ru
Russian Federation, Moscow

N. M. Gaifullin

M. V. Lomonosov Moscow State University

Email: dr.shegay@mail.ru
Russian Federation, Moscow

N. V. Vorob’ev

National Medical Radiological Research Center, Ministry of Health of the Russian Federation

Email: dr.shegay@mail.ru
Russian Federation, Moscow

B. Ya. Alekseev

National Medical Radiological Research Center, Ministry of Health of the Russian Federation

Email: dr.shegay@mail.ru
Russian Federation, Moscow

S. V. Popov

National Medical Radiological Research Center, Ministry of Health of the Russian Federation

Email: dr.shegay@mail.ru
Russian Federation, Moscow

A. V. Garazha

First Oncology Research and Advisory Center (FORAC)

Email: dr.shegay@mail.ru
Russian Federation, Moscow

A. A. Buzdin

First Oncology Research and Advisory Center (FORAC)

Email: dr.shegay@mail.ru
Russian Federation, Moscow

A. D. Kaprin

National Medical Radiological Research Center, Ministry of Health of the Russian Federation

Email: dr.shegay@mail.ru
Russian Federation, Moscow


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