Email this article Effect of Phytoadaptogen Administration during Early Ontogeny on Lifespan and Somatic Status of CBA Mice with High Incidence of Tumors
- Authors: Bocharov E.V.1, Karpova R.V.1, Bocharova O.A.1, Kucheryanu V.G.2, Shprakh Z.S.1
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Affiliations:
- N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
- Research Institute of General Pathology and Pathophysiology
- Issue: Vol 163, No 6 (2017)
- Pages: 789-792
- Section: Oncology
- URL: https://journals.rcsi.science/0007-4888/article/view/239268
- DOI: https://doi.org/10.1007/s10517-017-3904-x
- ID: 239268
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Abstract
We studied the influence of nontoxic phytoadaptogen complex on the lifespan and somatic status (body weight, coat state, and motor activity) of CBA mice predisposed to spontaneous hepatomas. Administration of the complex phytoadaptogen during the first month of postnatal ontogeny increased mean animal lifespan by 17.1% (p<0.001) and median of survival by 25.6% (p<0.001) and promoted maintenance of satisfactory physical status of CBA mice during spontaneous hepatocarcinogenesis.
About the authors
E. V. Bocharov
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
Email: planta39@rambler.ru
Russian Federation, Moscow
R. V. Karpova
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
Author for correspondence.
Email: planta39@rambler.ru
Russian Federation, Moscow
O. A. Bocharova
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
Email: planta39@rambler.ru
Russian Federation, Moscow
V. G. Kucheryanu
Research Institute of General Pathology and Pathophysiology
Email: planta39@rambler.ru
Russian Federation, Moscow
Z. S. Shprakh
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
Email: planta39@rambler.ru
Russian Federation, Moscow
