Effect of Phytoadaptogen Administration during Early Ontogeny on Lifespan and Somatic Status of CBA Mice with High Incidence of Tumors


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Resumo

We studied the influence of nontoxic phytoadaptogen complex on the lifespan and somatic status (body weight, coat state, and motor activity) of CBA mice predisposed to spontaneous hepatomas. Administration of the complex phytoadaptogen during the first month of postnatal ontogeny increased mean animal lifespan by 17.1% (p<0.001) and median of survival by 25.6% (p<0.001) and promoted maintenance of satisfactory physical status of CBA mice during spontaneous hepatocarcinogenesis.

Sobre autores

E. Bocharov

N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation

Email: planta39@rambler.ru
Rússia, Moscow

R. Karpova

N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation

Autor responsável pela correspondência
Email: planta39@rambler.ru
Rússia, Moscow

O. Bocharova

N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation

Email: planta39@rambler.ru
Rússia, Moscow

V. Kucheryanu

Research Institute of General Pathology and Pathophysiology

Email: planta39@rambler.ru
Rússia, Moscow

Z. Shprakh

N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation

Email: planta39@rambler.ru
Rússia, Moscow


Declaração de direitos autorais © Springer Science+Business Media, LLC, 2017

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