Email this article Anti-Inflammatory and Analgesic Activities of the Complex of Flavonoids from Lychnis chalcedonica L.
- Authors: Nesterova Y.V.1, Povet’eva T.N.1, Zibareva L.N.2, Suslov N.I.1,2, Zueva E.P.1, Aksinenko S.G.1, Afanas’eva O.G.1, Krylova S.G.1, Amosova E.N.1, Rybalkina O.Y.1,2, Lopatina K.A.1,2
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Affiliations:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
- National Research Tomsk State University
- Issue: Vol 163, No 2 (2017)
- Pages: 222-225
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238768
- DOI: https://doi.org/10.1007/s10517-017-3771-5
- ID: 238768
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Abstract
Anti-inflammatory and analgesic activities of the complex of flavonoids from Lychnis chalcedonica L. were studied in the models of acute aseptic inflammation induced by carrageenan, histamine, and serotonin and acetic acid-induced painful chemical stimulation. It is demonstrated that course treatment with flavonoids derived from Lychnis chalcedonica L. produced a stable pharmacological effect comparable with that of the reference anti-inflammatory drug diclofenac.
About the authors
Yu. V. Nesterova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Author for correspondence.
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk
T. N. Povet’eva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk
L. N. Zibareva
National Research Tomsk State University
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk
N. I. Suslov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center; National Research Tomsk State University
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk; Tomsk
E. P. Zueva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk
S. G. Aksinenko
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk
O. G. Afanas’eva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk
S. G. Krylova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk
E. N. Amosova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk
O. Yu. Rybalkina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center; National Research Tomsk State University
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk; Tomsk
K. A. Lopatina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center; National Research Tomsk State University
Email: nes-yuliya@yandex.ru
Russian Federation, Tomsk; Tomsk
