Anti-Inflammatory and Analgesic Activities of the Complex of Flavonoids from Lychnis chalcedonica L.


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Аннотация

Anti-inflammatory and analgesic activities of the complex of flavonoids from Lychnis chalcedonica L. were studied in the models of acute aseptic inflammation induced by carrageenan, histamine, and serotonin and acetic acid-induced painful chemical stimulation. It is demonstrated that course treatment with flavonoids derived from Lychnis chalcedonica L. produced a stable pharmacological effect comparable with that of the reference anti-inflammatory drug diclofenac.

Об авторах

Yu. Nesterova

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center

Автор, ответственный за переписку.
Email: nes-yuliya@yandex.ru
Россия, Tomsk

T. Povet’eva

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center

Email: nes-yuliya@yandex.ru
Россия, Tomsk

L. Zibareva

National Research Tomsk State University

Email: nes-yuliya@yandex.ru
Россия, Tomsk

N. Suslov

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center; National Research Tomsk State University

Email: nes-yuliya@yandex.ru
Россия, Tomsk; Tomsk

E. Zueva

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center

Email: nes-yuliya@yandex.ru
Россия, Tomsk

S. Aksinenko

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center

Email: nes-yuliya@yandex.ru
Россия, Tomsk

O. Afanas’eva

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center

Email: nes-yuliya@yandex.ru
Россия, Tomsk

S. Krylova

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center

Email: nes-yuliya@yandex.ru
Россия, Tomsk

E. Amosova

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center

Email: nes-yuliya@yandex.ru
Россия, Tomsk

O. Rybalkina

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center; National Research Tomsk State University

Email: nes-yuliya@yandex.ru
Россия, Tomsk; Tomsk

K. Lopatina

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center; National Research Tomsk State University

Email: nes-yuliya@yandex.ru
Россия, Tomsk; Tomsk


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