Email this article Effect of Transplantation of Mesenchymal Stem Cells on the Density of Pial Microvascular Network in Spontaneously Hypertensive Rats of Different Age
- Authors: Sokolova I.B.1, Sergeev I.V.1, Skorobogataya E.V.2, Ufimtseva A.N.2, Polyntsev D.G.2, Dvoretskii D.P.1
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Affiliations:
- Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
- Trans-Tekhnologii Company
- Issue: Vol 163, No 1 (2017)
- Pages: 129-132
- Section: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/238703
- DOI: https://doi.org/10.1007/s10517-017-3752-8
- ID: 238703
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Abstract
Using a TV device for studying microcirculation (×40), we analyzed the density of the whole microvascular network and the density of arterioles in the pia mater of the sensorimotor cortex in SHR rats of different ages (3-4 and 12 months) after intracerebral transplantation of human mesenchymal stem cells. We found that the density of pial microvascular network in SHR rats receiving transplantation of human mesenchymal stem cells increased to a level observed in young Wistar-Kyoto rats.
About the authors
I. B. Sokolova
Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
Author for correspondence.
Email: sib@kolt.infran.ru
Russian Federation, St. Petersburg
I. V. Sergeev
Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
Email: sib@kolt.infran.ru
Russian Federation, St. Petersburg
E. V. Skorobogataya
Trans-Tekhnologii Company
Email: sib@kolt.infran.ru
Russian Federation, St. Petersburg
A. N. Ufimtseva
Trans-Tekhnologii Company
Email: sib@kolt.infran.ru
Russian Federation, St. Petersburg
D. G. Polyntsev
Trans-Tekhnologii Company
Email: sib@kolt.infran.ru
Russian Federation, St. Petersburg
D. P. Dvoretskii
Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
Email: sib@kolt.infran.ru
Russian Federation, St. Petersburg
