Effect of Transplantation of Mesenchymal Stem Cells on the Density of Pial Microvascular Network in Spontaneously Hypertensive Rats of Different Age


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Using a TV device for studying microcirculation (×40), we analyzed the density of the whole microvascular network and the density of arterioles in the pia mater of the sensorimotor cortex in SHR rats of different ages (3-4 and 12 months) after intracerebral transplantation of human mesenchymal stem cells. We found that the density of pial microvascular network in SHR rats receiving transplantation of human mesenchymal stem cells increased to a level observed in young Wistar-Kyoto rats.

Sobre autores

I. Sokolova

Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences

Autor responsável pela correspondência
Email: sib@kolt.infran.ru
Rússia, St. Petersburg

I. Sergeev

Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences

Email: sib@kolt.infran.ru
Rússia, St. Petersburg

E. Skorobogataya

Trans-Tekhnologii Company

Email: sib@kolt.infran.ru
Rússia, St. Petersburg

A. Ufimtseva

Trans-Tekhnologii Company

Email: sib@kolt.infran.ru
Rússia, St. Petersburg

D. Polyntsev

Trans-Tekhnologii Company

Email: sib@kolt.infran.ru
Rússia, St. Petersburg

D. Dvoretskii

Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences

Email: sib@kolt.infran.ru
Rússia, St. Petersburg


Declaração de direitos autorais © Springer Science+Business Media, LLC, 2017

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