Email this article Analysis of Synergistic Effects of Antimicrobial Peptide Arenicin-1 and Conventional Antibiotics
- Authors: Bolosov I.A.1, Kalashnikov A.A.1, Panteleev P.V.1, Ovchinnikova T.V.1
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Affiliations:
- M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences
- Issue: Vol 162, No 6 (2017)
- Pages: 765-768
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238542
- DOI: https://doi.org/10.1007/s10517-017-3708-z
- ID: 238542
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Abstract
We studied combined effects of antimicrobial peptide arenicin-1 from lugworm Arenicola marina and some conventional antibiotics. A number of drug combinations with pronounced synergistic effects were revealed. The influence of antibacterial activity assessment conditions was determined and the methodology excluding false-positive test results was developed.
About the authors
I. A. Bolosov
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences
Email: ovch@ibch.ru
Russian Federation, Moscow
A. A. Kalashnikov
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences
Email: ovch@ibch.ru
Russian Federation, Moscow
P. V. Panteleev
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences
Email: ovch@ibch.ru
Russian Federation, Moscow
T. V. Ovchinnikova
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences
Author for correspondence.
Email: ovch@ibch.ru
Russian Federation, Moscow
