Analysis of Synergistic Effects of Antimicrobial Peptide Arenicin-1 and Conventional Antibiotics


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Resumo

We studied combined effects of antimicrobial peptide arenicin-1 from lugworm Arenicola marina and some conventional antibiotics. A number of drug combinations with pronounced synergistic effects were revealed. The influence of antibacterial activity assessment conditions was determined and the methodology excluding false-positive test results was developed.

Sobre autores

I. Bolosov

M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences

Email: ovch@ibch.ru
Rússia, Moscow

A. Kalashnikov

M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences

Email: ovch@ibch.ru
Rússia, Moscow

P. Panteleev

M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences

Email: ovch@ibch.ru
Rússia, Moscow

T. Ovchinnikova

M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences

Autor responsável pela correspondência
Email: ovch@ibch.ru
Rússia, Moscow


Declaração de direitos autorais © Springer Science+Business Media New York, 2017

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