Email this article Immunotropic Properties of Immobilized Interferon-α2b
- Authors: Sherstoboev E.Y.1, Shitikova O.G.1, Masnaya N.V.1, Danilets M.G.1, Trofimova E.S.1, Ligacheva A.A.1, Madonov P.G.2, Kinsht D.N.2, Ershov K.I.2, Shilova M.A.1
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Affiliations:
- E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine
- Siberian Center of Pharmacology and Biotechnology
- Issue: Vol 161, No 5 (2016)
- Pages: 693-697
- Section: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/237685
- DOI: https://doi.org/10.1007/s10517-016-3487-y
- ID: 237685
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Abstract
Course treatment with IFN-α2b immobilized on polyethylene glycol stimulates phagocytic activity of peritoneal macrophages and neutrophils, enhances humoral immune response in CBA/CaLac mice, stimulates IL-4 synthesis, and suppresses IFN-γ production by mitogenstimulated splenocytes from experimental animals.
About the authors
E. Yu. Sherstoboev
E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine
Author for correspondence.
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Tomsk
O. G. Shitikova
E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Tomsk
N. V. Masnaya
E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Tomsk
M. G. Danilets
E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Tomsk
E. S. Trofimova
E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Tomsk
A. A. Ligacheva
E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Tomsk
P. G. Madonov
Siberian Center of Pharmacology and Biotechnology
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Novosibirsk
D. N. Kinsht
Siberian Center of Pharmacology and Biotechnology
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Novosibirsk
K. I. Ershov
Siberian Center of Pharmacology and Biotechnology
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Novosibirsk
M. A. Shilova
E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine
Email: sherstoboev_eu@pharmso.ru
Russian Federation, Tomsk
