Immunotropic Properties of Immobilized Interferon-α2b

E. Yu. Sherstoboev; O. G. Shitikova; N. V. Masnaya; M. G. Danilets; E. S. Trofimova; A. A. Ligacheva; P. G. Madonov; D. N. Kinsht; K. I. Ershov; M. A. Shilova

doi:10.1007/s10517-016-3487-y

Immunotropic Properties of Immobilized Interferon-α2b

作者: Sherstoboev E.¹, Shitikova O.¹, Masnaya N.¹, Danilets M.¹, Trofimova E.¹, Ligacheva A.¹, Madonov P.², Kinsht D.², Ershov K.², Shilova M.¹
隶属关系:
1. E. D. Goldberg Research Institute of Pharmacology and Regenerativ Medicine
2. Siberian Center of Pharmacology and Biotechnology
期: 卷 161, 编号 5 (2016)
页面: 693-697
栏目: Microbiology and Immunology
URL: https://journals.rcsi.science/0007-4888/article/view/237685
DOI: https://doi.org/10.1007/s10517-016-3487-y
ID: 237685

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Course treatment with IFN-α2b immobilized on polyethylene glycol stimulates phagocytic activity of peritoneal macrophages and neutrophils, enhances humoral immune response in CBA/CaLac mice, stimulates IL-4 synthesis, and suppresses IFN-γ production by mitogenstimulated splenocytes from experimental animals.