Email this article Application of Laser Correlation Spectroscopy for Measuring Virus Size
- Authors: Nikiforov V.N.1, Vinogradov S.E.2, Ivanov A.V.2, Efremova E.V.3, Kalnina L.B.3, Bychenko A.B.4, Tentsov Y.Y.3, Manykin A.A.3
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Affiliations:
- Physical Faculty, M. V. Lomonosov Moscow State University
- N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
- D. I. Ivanovsky Institute of Virology, N. F. Gamaleya Federal Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
- M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides
- Issue: Vol 161, No 1 (2016)
- Pages: 88-91
- Section: Virology
- URL: https://journals.rcsi.science/0007-4888/article/view/237131
- DOI: https://doi.org/10.1007/s10517-016-3352-z
- ID: 237131
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Abstract
Dynamic light scattering method or laser correlation spectroscopy was applied to evaluation of the size of viruses. We measured correlation functions of the light scattered by human immunodeficiency viruses (HIV) and hepatitis A viruses (HAV) and found that size of HIV-1 (subtype A and B) and HAV virions were 104 nm and 28 nm, respectively. Comparison of these findings with electron microscopy data for fixed samples of the same viruses showed good agreement of the results.
About the authors
V. N. Nikiforov
Physical Faculty, M. V. Lomonosov Moscow State University
Author for correspondence.
Email: nvn@lt.phys.msu.ru
Russian Federation, Moscow
S. E. Vinogradov
N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Email: nvn@lt.phys.msu.ru
Russian Federation, Moscow
A. V. Ivanov
N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Email: nvn@lt.phys.msu.ru
Russian Federation, Moscow
E. V. Efremova
D. I. Ivanovsky Institute of Virology, N. F. Gamaleya Federal Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: nvn@lt.phys.msu.ru
Russian Federation, Moscow
L. B. Kalnina
D. I. Ivanovsky Institute of Virology, N. F. Gamaleya Federal Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: nvn@lt.phys.msu.ru
Russian Federation, Moscow
A. B. Bychenko
M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides
Email: nvn@lt.phys.msu.ru
Russian Federation, Moscow
Yu. Yu. Tentsov
D. I. Ivanovsky Institute of Virology, N. F. Gamaleya Federal Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: nvn@lt.phys.msu.ru
Russian Federation, Moscow
A. A. Manykin
D. I. Ivanovsky Institute of Virology, N. F. Gamaleya Federal Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: nvn@lt.phys.msu.ru
Russian Federation, Moscow
