Changes in Differentiation of Thymic T Cells in the Progeny of Female Mice Subjected to Immune System Stimulation during Early Pregnancy


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Abstract

Differentiation of T cells was studied in the progeny of female C57Bl/6 mice subjected to immunostimulation by administration of concanavalin A or adoptive transfer of concanavalin A-activated splenocytes. Acceleration of T cell maturation during the prepubertal period and decelerated differentiation during the pubertal and post-pubertal periods were revealed.

About the authors

N. V. Yaglova

Research Institute of Human Morphology

Author for correspondence.
Email: yaglova@mail.ru
Russian Federation, Moscow

S. S. Obernikhin

Research Institute of Human Morphology

Email: yaglova@mail.ru
Russian Federation, Moscow


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