Changes in Differentiation of Thymic T Cells in the Progeny of Female Mice Subjected to Immune System Stimulation during Early Pregnancy
- Authors: Yaglova N.V.1, Obernikhin S.S.1
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Affiliations:
- Research Institute of Human Morphology
- Issue: Vol 160, No 5 (2016)
- Pages: 664-667
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236870
- DOI: https://doi.org/10.1007/s10517-016-3244-2
- ID: 236870
Cite item
Abstract
Differentiation of T cells was studied in the progeny of female C57Bl/6 mice subjected to immunostimulation by administration of concanavalin A or adoptive transfer of concanavalin A-activated splenocytes. Acceleration of T cell maturation during the prepubertal period and decelerated differentiation during the pubertal and post-pubertal periods were revealed.
About the authors
N. V. Yaglova
Research Institute of Human Morphology
Author for correspondence.
Email: yaglova@mail.ru
Russian Federation, Moscow
S. S. Obernikhin
Research Institute of Human Morphology
Email: yaglova@mail.ru
Russian Federation, Moscow