Email this article Role of Nitric Oxide Produced by Lactobacilli in Relaxation of Intestinal Smooth Muscles
- Authors: Yarullina D.R.1, Mikheeva R.O.2, Sabirullina G.I.2, Zelenikhin P.V.1, Ilinskaya O.N.1, Sitdikova G.F.2
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Affiliations:
- Department of Microbiology, Kazan (Volga Region) Federal University
- Department of Human and Animal Physiology, Kazan (Volga Region) Federal University
- Issue: Vol 160, No 3 (2016)
- Pages: 343-346
- Section: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/236702
- DOI: https://doi.org/10.1007/s10517-016-3166-z
- ID: 236702
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Abstract
Application of NO-producing lactobacilli to a rat jejunum segment induced muscle relaxation that was potentiated after activation of bacterial NO production with NO synthase substrate L-arginine. Similar changes in the intestinal contractile activity were observed in response to exogenous NO formed by sodium nitroprusside. These results indicated the involvement of NO synthesized by probiotic lactobacilli in the regulation of the intestinal motor function.
About the authors
D. R. Yarullina
Department of Microbiology, Kazan (Volga Region) Federal University
Author for correspondence.
Email: kasfes@gmail.com
Russian Federation, Kazan
R. O. Mikheeva
Department of Human and Animal Physiology, Kazan (Volga Region) Federal University
Email: kasfes@gmail.com
Russian Federation, Kazan
G. I. Sabirullina
Department of Human and Animal Physiology, Kazan (Volga Region) Federal University
Email: kasfes@gmail.com
Russian Federation, Kazan
P. V. Zelenikhin
Department of Microbiology, Kazan (Volga Region) Federal University
Email: kasfes@gmail.com
Russian Federation, Kazan
O. N. Ilinskaya
Department of Microbiology, Kazan (Volga Region) Federal University
Email: kasfes@gmail.com
Russian Federation, Kazan
G. F. Sitdikova
Department of Human and Animal Physiology, Kazan (Volga Region) Federal University
Email: kasfes@gmail.com
Russian Federation, Kazan
