


Volume 52, Nº 4 (2018)
- Ano: 2018
- Artigos: 16
- URL: https://journals.rcsi.science/0006-3398/issue/view/14648
Theory and Design



Article
Experimental Studies of the Efficacy of Transmyocardial Laser Revascularization Using an Erbium Laser
Resumo
Results obtained using an erbium laser to produce directed angiogenesis in transmyocardial laser revascularization in experiments using an animal model of chronically ischemic myocardium are presented. An assessment of the efficacy of using the erbium laser to produce targeted angiogenesis is presented. The optimum operating regimes for erbium laser pulse irradiation of the myocardium, taking account of thermal tissue lesions, are identified. Morphological changes are investigated and morphometric analysis in tissues in the area of the transmyocardial laser channels are analyzed in a model of chronic ischemic heart disease (IHD) in dogs. Studies were performed for subsequent development and introduction of the new method into clinical practice in patients with IHD with diffuse coronary artery lesions.



The Effect of Pulsed Electric Field on the Generation of Charge in Flow-Based Medical and Diagnostic Systems
Resumo
The aim of this study is to consider the effect of pulsed electric field on the process of charge generation caused by motion of water in flow-based systems widely used in medical proteomic and diagnostic devices. It has been demonstrated that the use of pulsed electric field leads to an increase in the value of charge generated during the motion of the liquid (~ 80%, T = 35°С). The observed effect should be taken into account in the development of novel highly sensitive flow-based diagnostic systems



Antenna Applicators for Medical Microwave Radiometers
Resumo
The physical basis of microwave radiometry and the construction and technical characteristics of different types of antenna applicators used in medical radiometers are discussed. We present results obtained during the development and the potential uses of new types of antenna applicators in different areas of medicine.



Non-Medication-Based Apparatus for the Treatment of Lumbospinal Dorsopathy
Resumo
A means for non-medication-based treatment of spinal dorsopathy is described, specifically, using mechano-therapeutic DRX systems. The use of local internal disk-root decompression in 327 patients with lumbosacral dorsopathy, including 82.9% with disk hernias, is described. Measures of the efficacy of mechanotherapy are presented − results were excellent in 68.3%, good in 21.4%, and satisfactory in 7.1%.



Chemical Linking of Albumin to the Surface of Ion Beam-Modified Polyurethane Implants
Resumo
Polyurethane with a low modulus of elasticity for implantation into soft tissues was synthesized. Polyurethane was treated with nitrogen ions with energy 20 keV, which created a graphite-like layer on the surface of thickness about 56 nm, with active free radicals on the edges of the graphite planes. This resulted in covalent binding of a monolayer of albumin on the treated polyurethane surface as a result of free radical reactions.



Transmission Spectroscopy in Noninvasive Blood Glucose Measurement
Resumo
The use of laser diodes and photodiodes in transmission spectroscopy has some effects (temperature, time, spectral, and spatial) reducing the accuracy of glucose measurement. These effects can be reduced by using a (1600 ± 3) nm laser in combination with fixation and occlusion of the tissue area under examination. In this work, a method is suggested that allows spatial displacements of the system to be taken into account. A number of methods for reducing the effect of the thermal drift of the diodes are also suggested. A portable noninvasive optical glucose meter implemented using these methods provides high clinical performance: more than 97% of the measurements are in the A and B zones of the Parkes error grid.



Diagnosis of Anatomical Narrow Pelvis by Ultrasound Pelvimetry
Resumo
A comparative analysis of the effectiveness of pelvimetry is presented and a new method for ultrasound pelvimetry is proposed. Results showing that conventional pelvimetry is unreliable were obtained. A means of identifying clinical narrow pelvis was developed.



Assessment of Visual Acuity after Implantation of Gradient Multifocal Lenses
Resumo
The aims of the present work were to analyze existing methods of testing visual acuity and to undertake a comparative study of visual acuity at different distances after implantation of multifocal gradient intraocular lenses using modified ETDRS tables with Russian letters and the decimal system. The study data did not identify any statistically significant differences between measures of visual acuity obtained using the logarithmic and decimal systems. Use of ETDRS tables with Russian letters allows the procedure to be standardized for multinational clinical trials and exchange of databases.



Quantitative Assessment of the Quality of Treatment Planning for Patients with Advanced Cervical Cancer
Resumo
The indices of dose homogeneity and dose conformance for target volumes were calculated for 72 patients with stage 2-3 cervical cancer. Doses received by the bladder and the rectum were assessed for the patients in three groups. The first group received radiotherapy with intensity modulation in the rotational mode (RapidArc); the second group received intensity-modulated radiotherapy (IMRT); the third group, 3D conformal radiotherapy (3D CRT).The best homogeneity and conformance indices were obtained in the group receiving 3D CRT. The lowest dose loads on the rectum and the bladder were observed in the group receiving IMRT (36-58 Gy).



Modeling of Tissue Heating by Wireless Power Supply Units of Batteryless Implants
Resumo
The process of heating of surrounding tissues by a wireless power supply unit of batteryless implants with the output power of 500 mW was numerically simulated. The modeled medium consists of four layers: skin, fat, fascia, and muscle. The thicknesses of the layers are 2, 30, 1, and 25 mm, respectively. Heating was estimated for the cases of adiabatic and convective processes, for axially aligned antennas and for the lateral misalignment of the receiving antenna by 25 mm. The power of the heat sources in the first case was 117 mW (transmitting antenna), 6 mW (receiving antenna), and 109 mW (rectifier); in the second case − 210, 5, and 82 mW, respectively. Maximum heating level of the surrounding tissues did not exceed 1.56°С. It was found that planar packaging of the implantable part of the unit (the receiving antenna and the rectifier located in the same plane) reduces heating of the tissue because of better heat dissipation through the skin.



An Intelligent Decision Support System for Managing Patients with Lower Limb Ischemia Based on Hybrid Fuzzy Models
Resumo
The article discusses a mathematical model for predicting the occurrence and the course of development of ischemic lesions of the lower extremities, diagnosing the disease stages, and choosing rational prevention and treatment schedules based on the use of hybrid fuzzy mathematical models. The mathematical models suggested for this purpose use knowledge bases of intellectual systems for decision support in vascular surgery and angiology.



Titanium Nickelide Implants for Compression Anastomoses in Coloproctology
Resumo
Developments in titanium nickelide compression devices for forming interintestinal junctions in colorectal surgery are analyzed. Preference in developments has been given to compression devices made of titanium nickelide wire materials. The authors linked the main advantages with simplicity of use, small size, high levels of biological and physical sealing, and better conditions for tissue regeneration. Questions related to the means of establishing the primary patency of compression anastomoses and optimizing anastomosis techniques remain unanswered.






A Device for Determining the Optimum Graft Length in Reconstructive Microsurgery
Resumo
In this work, the principle of operation of a device for determination of the optimum length of grafts used in reconstructive surgery of damaged tendons, vessels, and nerves is described. Clinical tests of the device showed that it can be recommended for broad use.



An Automated System for Monitoring the Environment and Assessing People’s Status in Extreme Situations Using a Flying Robot
Resumo
Questions related to assessing the state of the environment using a small, flying, insect-like robot bearing an onboard environmental monitoring system with low power consumption are addressed. Data from the robot board are transmitted to an intelligent decision support system which also evaluates the level of ecological contamination and its effect on the state of health in humans operating in emergency zones.


