An Adaptive Algorithm for Machine Perfusion of Isolated Donor Liver

N. A. Gryaznov; V. V. Kharlamov; Ya. A. Gataulin; A. D. Yukhnev; A. V. Shumilov; S. A. Nikitin; K. Yu. Senchik; O. N. Reznik; A. E. Skvortsov

doi:10.1007/s10527-018-9758-3

An Adaptive Algorithm for Machine Perfusion of Isolated Donor Liver

Authors: Gryaznov N.A.¹, Kharlamov V.V.¹, Gataulin Y.A.², Yukhnev A.D.², Shumilov A.V.¹, Nikitin S.A.¹, Senchik K.Y.¹, Reznik O.N.³, Skvortsov A.E.¹
Affiliations:
1. Russian State Scientific Center for Robotics and Technical Cybernetics
2. Peter the Great St. Petersburg Polytechnic University
3. Pavlov First Saint Petersburg State Medical University
Issue: Vol 51, No 6 (2018)
Pages: 401-406
Section: Article
URL: https://journals.rcsi.science/0006-3398/article/view/235337
DOI: https://doi.org/10.1007/s10527-018-9758-3
ID: 235337

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Abstract

A hardware and software system for donor liver perfusion is described. Both standard and adaptive algorithms for perfusion control in the process of liver function restoration are described. The adaptive algorithm is based on a mathematical model of machine perfusion. It provides complete perfusion and allows blood cell injuries that often accompany the standard perfusion procedure to be avoided.