Email this article A Device and a Method for Determining the Rate of Oxygen Consumption by an Isolated Perfused Rat Liver
- Authors: Shadrin K.V.1,2, Pakhomova V.G.1, Kryukova O.V.1, Rupenko A.P.1
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Affiliations:
- Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences
- V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
- Issue: Vol 51, No 1 (2017)
- Pages: 52-55
- Section: Article
- URL: https://journals.rcsi.science/0006-3398/article/view/234890
- DOI: https://doi.org/10.1007/s10527-017-9683-x
- ID: 234890
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Abstract
The goal of this work was to suggest a method for measuring the total rate of oxygen consumption by an isolated perfused rat liver. This method involves calculation of the rates of oxygen consumption by the blood stream and through the liver surface. The two independently determined values are then summed up to determine the total consumption rate. Experimental results obtained by this method are in good agreement with the results obtained previously using the manometric method of measurement of the oxygen consumption rate.
About the authors
K. V. Shadrin
Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences; V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Author for correspondence.
Email: kvsh_buffon@mail.ru
Russian Federation, Krasnoyarsk; Krasnoyarsk
V. G. Pakhomova
Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences
Email: kvsh_buffon@mail.ru
Russian Federation, Krasnoyarsk
O. V. Kryukova
Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences
Email: kvsh_buffon@mail.ru
Russian Federation, Krasnoyarsk
A. P. Rupenko
Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences
Email: kvsh_buffon@mail.ru
Russian Federation, Krasnoyarsk
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