Therapeutic effects of high-dose inhaled nitric oxide gas against post-covid syndrome, diabetes or AIDS

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

A therapeutic effect of high-dose nitric oxide gas inhalation (more than 1000 ppm) on patients with post-COVID syndrome, diabetes or AIDS is shown. It has been proposed that nitrosonium cations (NO+), derivatives of nitric oxide gas, the emergence of which in the blood or organ tissues of patients is related to disproportion reaction of NO molecules, forming a co-ordinate bond with the Fe2+ion, carried by transferrin or entered into the labile (free) iron pool may act as a therapeutic agent. It is quite probable that treatment of HIV infection (as well as the earlier revealed effect of NO gas on the patients with COVID-19) could be provided by the effects of S-nitrosylation of NO+ cations on thiol groups of viral proteases and host proteins. A beneficial effect of NO+ cations which emerged in the reaction of NO gas molecules in patients with post-COVID syndrome or diabetes can be also associated with an inhibitory effect of these cations on the thiol-containig proteins that are involved in apoptosis.

Авторлар туралы

A. Vanin

N.N. Semenov Federal Research Center for Chemical Physics

Email: vanin.dnic@gmail.com
Moscow, Russia

A. Pekshev

N.E. Bauman Moscow State Technical University

Moscow, Russia

E. Pechyonkin

Stavropol State Medical University

Stavropol, Russia

A. Vagapov

N.E. Bauman Moscow State Technical University

Moscow, Russia

N. Sharapov

N.E. Bauman Moscow State Technical University

Moscow, Russia

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