Effect of alpha-fetoprotein on lifespan of old mice
- 作者: Krut’ko V.1,2, Dontsov V.1, Khalyavkin A.1
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隶属关系:
- Institute for Systems Analysis, Federal Research Center “Computer Science and Control”
- Sechenov First Moscow State Medical University
- 期: 卷 81, 编号 12 (2016)
- 页面: 1477-1479
- 栏目: Phenoptosis (Special Issue)
- URL: https://journals.rcsi.science/0006-2979/article/view/151142
- DOI: https://doi.org/10.1134/S0006297916120087
- ID: 151142
如何引用文章
详细
Alpha-fetoprotein (AFP) is one of the best-known embryo-specific proteins. It is used to diagnose fetal abnormalities and tumors of the gastrointestinal tract and liver. AFP has pronounced immunotropic and detoxifying effect and a direct apoptotic effect on tumor cells. The treatment of mice at the oldest age in our experiments with AFP dramatically increased the survival and markedly increased the relative weight of immunotropic organs, apparently due to the general effect of AFP in improving functions of tissues and detoxifying actions. It also improved appearance and the relative weight of internal organs with a reduced age of autoaggression.
作者简介
V. Krut’ko
Institute for Systems Analysis, Federal Research Center “Computer Science and Control”; Sechenov First Moscow State Medical University
Email: dontsovvi@mail.ru
俄罗斯联邦, Moscow, 117312; Moscow, 119991
V. Dontsov
Institute for Systems Analysis, Federal Research Center “Computer Science and Control”
编辑信件的主要联系方式.
Email: dontsovvi@mail.ru
俄罗斯联邦, Moscow, 117312
A. Khalyavkin
Institute for Systems Analysis, Federal Research Center “Computer Science and Control”
Email: dontsovvi@mail.ru
俄罗斯联邦, Moscow, 117312
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