Overview of fusion tags for recombinant proteins
- 作者: Kosobokova E.1, Skrypnik K.1, Kosorukov V.1
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隶属关系:
- Blokhin Russian Cancer Research Center
- 期: 卷 81, 编号 3 (2016)
- 页面: 187-200
- 栏目: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/150789
- DOI: https://doi.org/10.1134/S0006297916030019
- ID: 150789
如何引用文章
详细
Virtually all recombinant proteins are now prepared using fusion domains also known as “tags”. The use of tags helps to solve some serious problems: to simplify procedures of protein isolation, to increase expression and solubility of the desired protein, to simplify protein refolding and increase its efficiency, and to prevent proteolysis. In this review, advantages and disadvantages of such fusion tags are analyzed and data on both well-known and new tags are generalized. The authors own data are also presented.
作者简介
E. Kosobokova
Blokhin Russian Cancer Research Center
编辑信件的主要联系方式.
Email: ekkos@mail.ru
俄罗斯联邦, Moscow, 115478
K. Skrypnik
Blokhin Russian Cancer Research Center
Email: ekkos@mail.ru
俄罗斯联邦, Moscow, 115478
V. Kosorukov
Blokhin Russian Cancer Research Center
Email: ekkos@mail.ru
俄罗斯联邦, Moscow, 115478
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