Biogenesis of micronuclei
- Autores: Kisurina-Evgenieva O.1, Sutiagina O.1, Onishchenko G.1
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Afiliações:
- Lomonosov Moscow State University
- Edição: Volume 81, Nº 5 (2016)
- Páginas: 453-464
- Seção: Reviews
- URL: https://journals.rcsi.science/0006-2979/article/view/150869
- DOI: https://doi.org/10.1134/S0006297916050035
- ID: 150869
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Resumo
The presence of micronuclei in a cell is an indicator of DNA damage and genetic instability. In this review, mechanisms of emergence of micronuclei, their functional activity, and pathways of elimination are discussed. It is supposed that morphological and functional varieties of micronuclei as well as their degradation pathways can be determined by the chromosomal material localized inside these cell structures.
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Sobre autores
O. Kisurina-Evgenieva
Lomonosov Moscow State University
Autor responsável pela correspondência
Email: evgengeva@mail.ru
Rússia, Moscow, 119234
O. Sutiagina
Lomonosov Moscow State University
Email: evgengeva@mail.ru
Rússia, Moscow, 119234
G. Onishchenko
Lomonosov Moscow State University
Email: evgengeva@mail.ru
Rússia, Moscow, 119234