Email this article Biogenesis of micronuclei
- Authors: Kisurina-Evgenieva O.P.1, Sutiagina O.I.1, Onishchenko G.E.1
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Affiliations:
- Lomonosov Moscow State University
- Issue: Vol 81, No 5 (2016)
- Pages: 453-464
- Section: Reviews
- URL: https://journals.rcsi.science/0006-2979/article/view/150869
- DOI: https://doi.org/10.1134/S0006297916050035
- ID: 150869
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Abstract
The presence of micronuclei in a cell is an indicator of DNA damage and genetic instability. In this review, mechanisms of emergence of micronuclei, their functional activity, and pathways of elimination are discussed. It is supposed that morphological and functional varieties of micronuclei as well as their degradation pathways can be determined by the chromosomal material localized inside these cell structures.
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About the authors
O. P. Kisurina-Evgenieva
Lomonosov Moscow State University
Author for correspondence.
Email: evgengeva@mail.ru
Russian Federation, Moscow, 119234
O. I. Sutiagina
Lomonosov Moscow State University
Email: evgengeva@mail.ru
Russian Federation, Moscow, 119234
G. E. Onishchenko
Lomonosov Moscow State University
Email: evgengeva@mail.ru
Russian Federation, Moscow, 119234
