Email this article Evaluating the efficiency of cell mechanisms and systems
- Authors: Novikov K.A.1,2, Romanyukha A.A.1,3
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Affiliations:
- Moscow State University
- Federal Research Institute for Health Organization and Informatics
- Institute of Computational Mathematics
- Issue: Vol 77, No 5 (2016)
- Pages: 862-871
- Section: Control in Social Economic Systems, Medicine, and Biology
- URL: https://journals.rcsi.science/0005-1179/article/view/150346
- DOI: https://doi.org/10.1134/S000511791605009X
- ID: 150346
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Abstract
We propose an approach for estimating the efficiency of biological systems and mechanisms in vivo. We compare two mechanisms for chemical transport: diffusion and endosome transport with a cargo along a system of microtubules. Our efficiency evaluation is based on a comparison of the organism’s energy expenditure for cell house-keeping and the transport system’s operation with the speed of cargo delivery. We study the relation between transport efficiency and adaptability of the transport network. Our approach can be used to study models of live systems and solve problems of artificial life design.
About the authors
K. A. Novikov
Moscow State University; Federal Research Institute for Health Organization and Informatics
Author for correspondence.
Email: konst.novikov@gmail.com
Russian Federation, Moscow; Moscow
A. A. Romanyukha
Moscow State University; Institute of Computational Mathematics
Email: konst.novikov@gmail.com
Russian Federation, Moscow; Moscow
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