COMPARISON OF DIFFERENT METHOD OF ANALGESIA IN AGED PATIENTSWITH CHRONIC LOW BACK PAIN

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Abstract

Effectiveness of different methods of analgesia was studied in 34 aged patients suffering chronic low back pain. All patients were at age 60 to 86 and were randomized into N-group in which nefopam (60 mg rectally) was administrated and K-group that included patients who received ketoprofen (100 mg rectally). The end-points of this prospective study were decrease of pain intensity after analgesics administration, contentment of therapy, and characteristics of side effects of medications taking (twice daily for three days). We found that pain intensity decreases by 6,3±1,6 in N-group and 6,1±1,3 in K- group (p<0.05 in the both cases) and achieves 0,9±1,4 and 0,9±1,6 in N- and in K-group, respectively (p>0.05 in comparison between groups). No significant differences between groups were in estimation of therapy contentment. No side effects were registered. Thus, our data proved the equal effectiveness of central nonopioid analgesic nefopam and nonselective cyclooxygenise inhibitor ketoprofen for achievement of good analgesia in aged patients with chronic low back pain.

About the authors

G N Vasilieva

North-Western State Medical university n.a. I.I. Mechnikov

A L Linkov

North-Western State Medical university n.a. I.I. Mechnikov

N O Kukushkina

North-Western State Medical university n.a. I.I. Mechnikov

F I Dimitrienko

North-Western State Medical university n.a. I.I. Mechnikov

A E Karelov

North-Western State Medical university n.a. I.I. Mechnikov

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Copyright (c) 2017 Vasilieva G.N., Linkov A.L., Kukushkina N.O., Dimitrienko F.I., Karelov A.E.

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