Prostatic Hyperplasia and Urethral Stricture as Comorbid Factors of Infravesical Obstruction

Prostatic hyperplasia and urethral strictures are the most common causes of infravesical obstruction. These disorders are typically studied in isolation, without consideration of their potential coexistence in a single patient, which leads to insufficient awareness of the combined condition of the urethra, prostate, and bladder. This review analyzes the scientific data published between 2020 and 2024 that addresses infravesical obstruction caused by the combination of prostatic hyperplasia and urethral stricture. Scientific sources were searched in both Russian (eLibrary) and international (PubMed, Embase, Cochrane Library, Web of Science, Scopus) databases. The following keywords were used: стриктура уретры (urethral stricture), доброкачественная гиперплазия предстательной железы (benign prostatic hyperplasia), инфравезикальная обструкция (infravesical obstruction), симптомы нижних мочевых путей (lower urinary tract symptoms), хроническая задержка мочи (chronic urinary retention), хирургическое лечение (surgical treatment), and послеоперационные осложнения (postoperative complications). Only a limited number of publications were found that discuss clinical scenarios where infravesical obstruction is simultaneously caused by both prostatic hyperplasia and urethral stricture. Treatment strategies for such patients should be based on a functional and anatomical assessment of the lower urinary tract, which may vary significantly in each case. An individualized approach is required when managing patients with this comorbidity. The lack of large-scale studies limits the ability to obtain meaningful data necessary for developing treatment guidelines for the concurrent management of both conditions.