Regarding the efficacy of low-level laser therapy in infrared spectrum in male secretory infertility

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Abstract

The aim of study was to assess the effect of low-level laser therapy (LLLT) in infrared spectrum on the main sperm parameters, sperm DNA fragmentation, MAR-test in men with nonobstructive pathozoospermia.

Patients and methods. The study included 50 men from 23 to 40 years old (average age 31.0 ± 5.4), suffering from secretory infertility. Physical examination, semen analysis, MAR-test, sperm DNA fragmentation analysis, male hormone panel, assessment of prostate microbiocenosis, testes and prostate tumor markers, ultrasound examination with color flow mapping were performed. After the examination patients had a course of LLLT in infrared spectrum on a Rubin-C device. 10 laser therapy procedures were carried out every two days with active luminescence for 3 minutes of both testicles. Control examination was done immediately after the LLLT, within one and two months.

Results. Increase in sperm concentration (by an average of 25%), active mobile sperm forms (by an average of 25%), morphologically normal sperm forms (by an average of 58%) was noticed after the LLLT. MAR-test decreased by an average of 69% after the therapy. From 10 patients with initially increased sperm DNA fragmentation level, in 9 patients its level became normal after the treatment. Increase in concentration of total and free testosterone in blood plasma was noticed within one month after the LLLT. As a result of the treatment pregnancies developed in 11 (22%) out of 50 couples.

Conclusions. LLLT in infrared spectrum improves sperm quality in patients with secretory infertility, decreases MAR-test level, normalizes sperm DNA-fragmentation level, increases chances of pregnancy in reproductive cycle, which allows to recommend this method as preparation for assisted reproductive technologies.

About the authors

Maria K. Potapova

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation

Author for correspondence.
Email: maria.potapova.92@mail.ru

Postgraduate Student, Department of Urology

Russian Federation, Saint Petersburg

Sergey Yu. Borovets

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation

Email: sborovets@mail.ru

Doctor of Medical Science, Professor, Department of Urology

Russian Federation, Saint Petersburg

Arkadiy V. Sokolov

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation

Email: sok003@yandex.ru

Head of the Department of Laser Medicine, Urologist

Russian Federation, Saint Petersburg

Salman Kh. Al-Shukri

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation

Email: alshukri@mail.ru

Doctor of Medical Science, Professor, Head of the Department of Urology

Russian Federation, Saint Petersburg

Vladimir N. Tkachuk

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation

Email: tkachuk1@yandex.ru

Doctor of Medical Science, Professor, Honored Science Worker of Russian Federation, Department of Urology

Russian Federation, Saint Petersburg

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Copyright (c) 2020 Potapova M.K., Borovets S.Y., Sokolov A.V., Al-Shukri S.K., Tkachuk V.N.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
 


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