Email this article Annual trends in semen parameters among men attending a fertility center between 2016 and 2022
- Authors: Korneyev I.A.1,2
-
Affiliations:
- Academician I.P. Pavlov First St. Petersburg State Medical University
- JSC “International Center for Reproductive Medicine”
- Issue: Vol 13, No 1 (2023)
- Pages: 23-29
- Section: Original articles
- URL: https://journals.rcsi.science/uroved/article/view/134242
- DOI: https://doi.org/10.17816/uroved296569
- ID: 134242
Cite item
Open Access
Access granted
Subscription Access
Abstract
BACKGROUND: Multiple studies have shown sperm concentration and count decline in many countries, however, authors’ conclusions were inconsistent. These types of studies were not conducted in Russia so far.
AIM: To evaluate and analyze semen parameters among men attending a fertility center in St. Petersburg between 2016 and 2022.
MATERIALS AND METHODS: In a retrospective study parameters of 14234 consequent semen analyses performed according to WHO guidelines (2010) were sorted, analyzed and compared by year.
RESULTS: The distribution parameters of the ejaculate volume did not have change over observation period. Azoospermia and cryptozoospermia were detected in 597 (4.2%) and 435 (3.1%) men respectively. A downward trends for sperm concentration of 1.6 million/ml (1.9%)/year and sperm count of 7 million (1.8%)/year were found, with simultaneous annual increase of 1.3% in the proportion of progressively motile spermatozoa. No noticeable changes in the number of motile spermatozoa and the proportion of spermatozoa with normal morphology were found.
CONCLUSIONS: Further research is needed to obtain final conclusions about the gradual decline in the semen quality and reproductive function of men, also in other centers of the Russian Federation.
Full Text
##article.viewOnOriginalSite##About the authors
Igor A. Korneyev
Academician I.P. Pavlov First St. Petersburg State Medical University; JSC “International Center for Reproductive Medicine”
Author for correspondence.
Email: iakorneyev@yandex.ru
ORCID iD: 0000-0001-7347-1901
SPIN-code: 4780-2266
Scopus Author ID: 6506000592
ResearcherId: R-3046-2017
https://professiya-vrach.ru/heroes/sankt-peterburg/korneev-igor-alekseevich/
Dr. Sci. (Med.), professor of the Department of Urology
Russian Federation, Saint Petersburg; Saint PetersburgReferences
- Nosova GG, Fedortsova YV, Morev VV, Korneyev IA. Male infertility risk factors in men seeking care in art center. Urologicheskie vedomosti. 2013;3(3):18–21. (In Russ.) doi: 10.17816/uroved3318-21
- Eisenberg ML, Li S, Cullen MR, Baker LC. Increased risk of incident chronic medical conditions in infertile men: analysis of United States claims data. Fertil Steril. 2016;105(3):629–636. doi: 10.1016/j.fertnstert.2015.11.011
- Jensen TK, Jacobsen R, Christensen K, et al. Good semen quality and life expectancy: a cohort study of 43,277 men. Am J Epidemiol. 2009;170(5):559–565. doi: 10.1093/aje/kwp168
- Carlsen E, Giwercman A, Keiding N, Skakkebaek NE. Evidence for decreasing quality of semen during past 50 years. BMJ. 1992;305(6854):609–613. doi: 10.1136/bmj.305.6854.609
- Swan SH, Elkin EP, Fenster L. Have sperm densities declined? A reanalysis of global trend data. Environ Health Perspect. 1997;105(11):1228–1232. doi: 10.1289/ehp.971051228
- Levine H, Jørgensen N, Martino-Andrade A, et al. Temporal trends in sperm count: a systematic review and meta-regression analysis. Hum Reprod Update. 2017;23(6):646–659. doi: 10.1093/humupd/dmx022
- Levine H, Jørgensen N, Martino-Andrade A, et al. Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries. Hum Reprod Update. 2023;29(2):157–176. doi: 10.1093/humupd/dmac035
- Cipriani S, Ricci E, Chiaffarino F, et al. Trend of change of sperm count and concentration over the last two decades: A systematic review and meta-regression analysis. Andrology. 2023. doi: 10.1111/andr.13396
- Lv MQ, Ge P, Zhang J, et al. Temporal trends in semen concentration and count among 327 373 Chinese healthy men from 1981 to 2019: a systematic review. Hum Reprod. 2021;36(7):1751–1775. doi: 10.1093/humrep/deab124
- https://www.who.int/ru/news-room/fact-sheets/detail/infertility
- Agarwal A, Mulgund A, Hamada A, Chyatte MR. A unique view on male infertility around the globe. Reprod Biol Endocrinol. 2015;13:37. doi: 10.1186/s12958-015-0032-1
- Cooper TG, Noonan E, von Eckardstein S, et al. World Health Organization reference values for human semen characteristics. Hum Reprod Update. 2010;16(3):231–245. doi: 10.1093/humupd/dmp048
- Xie Y, Mirzaei M, Kahrizi MS, et al. SARS-CoV-2 effects on sperm parameters: a meta-analysis study. J Assist Reprod Genet. 2022;39(7):1555–1563. doi: 10.1007/s10815-022-02540-x
- Hamilton JA, Cissen M, Brandes M, et al. Total motile sperm count: a better indicator for the severity of male factor infertility than the WHO sperm classification system. Hum Reprod. 2015;30(5): 1110–1121. doi: 10.1093/humrep/dev058
Supplementary files
