Nocturnal enuresis — a new look at the old problem
- Authors: Smirnova N.N.1, Belyakova A.V.1, Kuprienko N.B.1, Nikolskaya T.I.1
-
Affiliations:
- Academician I.P. Pavlov First St. Petersburg State Medical University
- Issue: Vol 12, No 4 (2022)
- Pages: 347-356
- Section: Reviews
- URL: https://journals.rcsi.science/uroved/article/view/134236
- DOI: https://doi.org/10.17816/uroved112569
- ID: 134236
Cite item
Abstract
Nocturnal enuresis is the most common functional disorder of the urinary system in children, significantly reducing the quality of life of both patients and their parents. There are several hypotheses for the development of this disease, none of which can be taken as dominant. In this regard, Nocturnal enuresis is considered as a polyetiological condition. This review details the main factors that are associated with the development of nocturnal enuresis in children. These include hereditary predisposition, bladder dysfunction, sleep and awakening disorders, delayed maturation of central nervous system structures, disruption of the circadian rhythm of antidiuretic hormone and aquaporin-2 production. Despite many publications on nocturnal enuresis in children, many aspects of the pathogenesis of the disease remain unclear and require further study.
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##article.viewOnOriginalSite##About the authors
Natalia N. Smirnova
Academician I.P. Pavlov First St. Petersburg State Medical University
Author for correspondence.
Email: nephro-uro-kids@mail.ru
ORCID iD: 0000-0002-0581-7285
SPIN-code: 4518-0640
Dr. Sci. (Med.), Professor, Head of the Department of Pediatrics
Russian Federation, Saint PetersburgAlla V. Belyakova
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: belalla@mail.ru
SPIN-code: 1702-0720
Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics
Russian Federation, Saint PetersburgNatalia B. Kuprienko
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: n-b-k@bk.ru
ORCID iD: 0000-0003-2054-3419
SPIN-code: 3394-8106
Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics
Russian Federation, Saint PetersburgTatyana I. Nikolskaya
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: t.nikol@mail.ru
Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics
Russian Federation, Saint PetersburgReferences
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