Pathogenetic aspects of male subfertility in obesity: a review of experimental and clinical studies

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Abstract

The obesity epidemic in the 21st century is an actual public health problem. The obesity is the cause of many pathological conditions in humans. According to the latest data there is a link between reproductive health and obesity, in particular, with a decrease in the quality and quantity of ejaculate in men. Nevertheless information about the effect of obesity on the parameters of spermogram is controversial. The purpose of this review was to study the relationship of body mass index with sperm parameters in animal experiments and indicators in men of reproductive age. This article reviewed the results of studies conducted on animals, as well as systematic reviews of studies conducted in a clinical setting.

About the authors

Ljubov M. Jakovleva

Chuvash State University named after I.N. Ulyanov of the Ministry of Science and Higher Education of the Russian Federation

Email: 28Lybov@mail.ru

Doctor of Biological Science, Professor of Department of Normal and Pathological Physiology

Russian Federation, Cheboksary

Vjacheslav V. Porfiriev

Chuvash State University named after I.N. Ulyanov of the Ministry of Science and Higher Education of the Russian Federation

Author for correspondence.
Email: kypol55@gmail.com

Assistant of Department of Normal and Pathological Physiology

Russian Federation, Cheboksary

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