Microsurgical toe-to-hand transfer in children with macrodactyly of the hand
- 作者: Golyana S.I.1, Tikhonenko T.I.1, Govorov A.V.1, Zaytseva N.V.1
-
隶属关系:
- The Turner Scientific Research Institute for Children’s Orthopedics
- 期: 卷 6, 编号 3 (2018)
- 页面: 32-39
- 栏目: Original papers
- URL: https://journals.rcsi.science/turner/article/view/10225
- DOI: https://doi.org/10.17816/PTORS6332-39
- ID: 10225
如何引用文章
详细
Background. At present, there are multiple approaches to the treatment of macrodactylia in children. Additionally, there are no comparative data on the cosmetic and functional aspects of corrective surgery versus microsurgical transplantations performed in children with a marked disproportion of the segment, making this study particularly relevant.
Aim. The aim of this study was to determine the role of microsurgical transplantation of the toes in the treatment of children with isolated macrodactylia, based on a comparative analysis of various surgical interventions.
Materials and methods. Twenty-five children with congenital macrodactylia of the hand were examined and surgically treated in the department of reconstructive microsurgery from 2013 to 2017. Of these, 13 (52%) had macrodactyly of the 2nd and/or 3rd fingers, and of the total number of hyperplastic hand segments (n = 45), 17 rays had hyperplasia greater than 25%.
Results and discussion. Stage-by-stage modeling resections of enlarged segments were performed in all children with ray hyperplasia that was about 25% of the size of intact fingers. In 4 cases, excision of soft tissues was combined with marginal resection of phalanges. When hyperplasia of the segment reached up to 10% of macrodactylia, single isolated modeling resection of soft tissues and bones was performed. Repeated modeling plasties in 16% (n = 4) of the children were accompanied by gross postoperative scars with the development of secondary angular deformities and loss of function of interphalangeal joints.
Nine children (n = 14) underwent amputation of hyperplastic fingers followed by microsurgical reconstruction of rays by autografting of toes. In 4 cases, the first finger was reconstructed, and in the other 5 cases, toes of both feet were transplanted to the positions 2 and 3 (n = 4) or 3 and 4 of fingers (n = 1). It was found that in cases of significant hyperplasia of the affected segments of the hand (hyperplastic segment is 1.5–2 times greater compared to normal ones), microsurgical autografting of toes is more effective and acceptable compared to bone and soft tissue resections.
Conclusions. In cases of segment hyperplasia less than 1.25-times the normal size, the optimal surgical interventions are stage-by-stage modeling resections. An alternative surgical treatment for children with hyperplasia of more than 1.25-times the normal size is microsurgical transplantation of the toes in the position of the involved rays of the hand, which results in good cosmetic and functional outcomes in these patients.
作者简介
Sergey Golyana
The Turner Scientific Research Institute for Children’s Orthopedics
编辑信件的主要联系方式.
Email: ser.golyana@yandex.ru
MD, PhD, Scientific Supervisor Department of Reconstructive Microsurgery and Hand Surgery
俄罗斯联邦, 64, Parkovaya str., Saint-Petersburg, Pushkin, 196603Tatiana Tikhonenko
The Turner Scientific Research Institute for Children’s Orthopedics
Email: Tikhonenko_turner@mail.ru
MD, PhD, Leading Research Associate of the Department of Reconstructive Microsurgery and Hand Surgery
俄罗斯联邦, 64, Parkovaya str., Saint-Petersburg, Pushkin, 196603Anton Govorov
The Turner Scientific Research Institute for Children’s Orthopedics
Email: agovorov@yandex.ru
MD, PhD, Orthopedic and Trauma Surgeon of the Department of Trauma Effects and Rheumatoid Arthritis
64, Parkovaya str., Saint-Petersburg, Pushkin, 196603Natal’ya Zaytseva
The Turner Scientific Research Institute for Children’s Orthopedics
Email: zaiceva.n@mail.ru
MD, Anesthesiologist-Resuscitator of the Department of Anesthesiology, Resuscitation and Intensive Care
俄罗斯联邦, 64, Parkovaya str., Saint-Petersburg, Pushkin, 196603参考
- Congenital Anomalies of the Upper Extremity. Etiology and Management. Ed by D.R. Laub. Boston: Springer; 2015. doi: 10.1007/978-1-4899-7504-1.
- Cerrato F, Eberlin KR, Waters P, et al. Presentation and treatment of macrodactyly in children. J Hand Surg Am. 2013;38(11):2112-2123. doi: 10.1016/j.jhsa.2013.08.095.
- Gluck JS, Ezaki M. Surgical Treatment of Macrodactyly. J Hand Surg Am. 2015;40(7):1461-1468. doi: 10.1016/j.jhsa.2015.04.017.
- The Care of Congenital Hand Anomalies. Ed by A.E. Flatt, W.H.J. Chang. 2nd ed. St. Louis: Quality Medical Publishers, Inc; 1994.
- Omim.org [Internet]. Online Mendelian Inheritance in Man [cited 2018 May 12]. Available from: www.omim.org.
- Keppler-Noreuil KM, Rios JJ, Parker VE, et al. PIK3CA-related overgrowth spectrum (PROS): diagnostic and testing eligibility criteria, differential diagnosis, and evaluation. Am J Med Genet A. 2015;167A(2):287-295. doi: 10.1002/ajmg.a.36836.
- Miller TW, Rexer BN, Garrett JT, Arteaga CL. Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer. Breast Cancer Res. 2011;13(6):224. doi: 10.1186/bcr3039.
- Flatt AE. Large fingers. In: The Care of Congenital Hand Anomalies. Ed by A.E. Flatt, W.H.J. Chang. 2nd ed. St Louis: Quality Medical Publishing; 1994. P. 317-333.
- Upton J. Failure of differentiation and overgrowth. In: Plastic surgery. Ed by S.J. Mathes. 2nd ed. Philadelphia: Saunders Elsevier; 2006. p. 265-322.
- Rayan GM, Upton III J. Overgrowth (Macrodactyly). In: Congenital Hand Anomalies and Associated Syndromes. Berlin, Heidelberg: Springer; 2014. P. 215-245. doi: 10.1007/978-3-642-54610-5_17.
- Dell PC. Macrodactyly. Hand Clin. 1985;1(3):511-524.
- Kelikian H. Congenital deformities of the hand and forearm. Philadelphia: WB Saunders; 1974.
- Сосненко О.Н. Истинный врожденный гигантизм кисти у детей: Дис. ... канд. мед. наук. – СПб., 2002. [Sosnenko ON. Istinnyi vrozhdennyi gigantizm kisti u detey. [dissertation] Saint Petersburg; 2002. (In Russ.)]
- Микрохирургическое лечение детей с истинным врожденным гигантизмом кисти: Пособие для врачей. – СПб., 2004. [Mikrokhirurgicheskoe lechenie detey s istinnym vrozhdennym gigantizmom kisti. Posobie dlya vrachey. Saint Petersburg; 2004. (In Russ.)]
- Шведовченко И.В. Лечение детей с врожденными пороками развития верхних конечностей //Травматология и ортопедия: руководство для врачей: в 4 т. Т. 2: Травмы и заболевания плечевого пояса и верхней конечности / Под ред. Н.В. Корнилова и Э.Н. Грязнухина. – СПб.: Гиппократ, 2005. [Shvedovchenko IV. Lechenie detey s vrozhdennymi porokami razvitiya verkhnikh konechnostey. In: Travmatologiya i ortopediya: rukovodstvo dlya vrachey: v 4 t. Ed by N.V. Kornilov, E.N. Gryaznukhin. T. 2: Travmy i zabolevaniya plechevogo poyasa i verkhnei konechnosti. Saint Petersburg: Gippokrat; 2005. (In Russ.)]
- Шведовченко И.В. Врожденные пороки развития кисти. Общие положения микрохирургических реконструкций // Вопросы реконструктивной и пластической хирургии. – 2017. – Т. 20. – № 1. – С. 28–35. [Shvedovchenko IV. Congenital malformations of hand evolution. general statutes of microsurgical reconstructions. Issues of reconstructive and plastic surgery. 2017;20(1):28-35. (In Russ.)]. doi: 10.17223/1814147/60/03.
- Cavadas PC, Thione A. Treatment of Hand Macrodactyly With Resection and Toe Transfers. J Hand Surg Am. 2018;43(4):388.e381-388.e386. doi: 10.1016/j.jhsa.2017.08.012.
补充文件
