The features of the pollen sensitization in seasonal allergic rhinitis patients with gastrointestinal tract inflammatory diseases comorbidity
- 作者: Iraklionova N.1, Belan E.1, Turkina S.1, Panina A.1,2, Sadchikova T.1, Klyausov A.1
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隶属关系:
- Volgograd State Medical University
- Consultative Diagnostic Clinics № 2
- 期: 卷 17, 编号 3 (2020)
- 页面: 57-63
- 栏目: Original studies
- URL: https://journals.rcsi.science/raj/article/view/121613
- DOI: https://doi.org/10.36691/RJA1371
- ID: 121613
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BACKGROUND: Allergic diseases and gastrointestinal tract diseases can influence on the natural course of each other.
AIM: To study the sensitization profile in patients with comorbidity of seasonal allergic rhinitis (SAR) and upper gastrointestinal tract inflammatory diseases (UGITID).
MATERIALS AND METHODS: 112 adult residents of Volgograd city suffering from SAR but without perennial symptoms and sensitization to indoor allergens have been included in the study. 31/112 patients had H. pylori-negative and 38/112 H. pylori-positive UGITID. Control group consisted of 43/112 patients without gastrointestinal diseases. Skin prick-testing with 3 groups of pollen allergens have been carried out.
RESULTS: 75.9% of patients were sensitized to weed pollen; sensitization to grass pollen was in 1.5–3 times less, and 10.5% of patients (4/38) had positive tests with birch pollen. The sensitization to quinoa and ragweed in SAR and H. pylori«–»-UGITID patients was comparable with control group but less common with wormwood, sumpfweed allergens. The sensitization in SAR patients and H. pylori«+»-UGITID was similar to the control group, but positive SPT with sunflower and corn allergens were rare then in control group.
CONCLUSION: Weed pollen allergens prevail in sensitization spectrum of adult Volgograd residents with SAR. Sensitization to goose-foot and ragweed is common less in SAR patients and H. pylori«–»-UGITID but to graminea grass and birch pollen is more often. It may be supposed that the UGITID are predisposing factors to the sensitization to cross-reacting plant food allergens. At the same time supposed immunomodulating action of H. pylori make the differences between AR patients with H. pylori«+»-UGITID or H. pylori«–»-UGITID minor.
作者简介
Natalia Iraklionova
Volgograd State Medical University
Email: ins2904@rambler.ru
ORCID iD: 0000-0003-3186-260X
assistant of the Department of Immunology and Allergology, Volgograd State Medical University
俄罗斯联邦, VolgogradEleonora Belan
Volgograd State Medical University
编辑信件的主要联系方式.
Email: belan.eleonora@yandex.ru
ORCID iD: 0000-0003-2674-4289
head of the Department of Immunology and Allergology, Volgograd State Medical University MD, PhD, Professor
俄罗斯联邦, VolgogradSvetlana Turkina
Volgograd State Medical University
Email: turkinasv@rambler.ru
ORCID iD: 0000-0002-8844-2465
pofessor of the Department of Internal Medicine of the Pediatrics and Dental Faculties, Volgograd State Medical University, MD, PhD
俄罗斯联邦, VolgogradAnna Panina
Volgograd State Medical University; Consultative Diagnostic Clinics № 2
Email: godkota@rambler.ru
ORCID iD: 0000-0003-2750-8579
head of the Consultative Diagnostic Clinic № 2, Volgograd, PhD
俄罗斯联邦, VolgogradTatiana Sadchikova
Volgograd State Medical University
Email: sadchikovatl@mail.ru
ORCID iD: 0000-0001-5762-0196
associate professor of the Immunology and Allergology Department, Volgograd State Medical University, PhD
俄罗斯联邦, VolgogradAndrey Klyausov
Volgograd State Medical University
Email: ak-flash@mail.ru
ORCID iD: 0000-0003-1631-6010
associate professor of the Immunology and Allergology Department, Volgograd State Medical University, PhD
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