Efficiency of montelukast in control of atopic diseases at children of preschool age
- 作者: Volkova NA1, Beltyukov EK2
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隶属关系:
- Central Medical-Sanitary Department № 91 of the FMBA of Russia
- Ural State Medical University Ministry of Health of Russia
- 期: 卷 12, 编号 1 (2015)
- 页面: 49-52
- 栏目: Articles
- URL: https://journals.rcsi.science/raj/article/view/120838
- DOI: https://doi.org/10.36691/RJA485
- ID: 120838
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详细
The aim of study. To estimate clinical efficiency of the antagonist of the leukotriiene receptors - montelukast in control of atopic diseases at children of preschool age. Materials and methods. Open randomized comparative study of clinical efficiency of montelukast in parallel groups of children of preschool age having atopic diseases was conducted. Results. Inclusion of montelukast (singular) in basic therapy of children of preschool age, having atopic diseases, allowed to decrease the number of exacerbations of a bronchial asthma and allergic rhinitis and as well as the necessity of «emergency aid», when a dose of topical glucocorticosteroids reduced 1,9 times. Conclusion. Montelukast treatment showed high clinical efficiency and allowed to control symptoms of allergic rhinitis and bronchial asthma, when it was included in the basic therapy of atopic diseases at children of preschool age.
作者简介
N Volkova
Central Medical-Sanitary Department № 91 of the FMBA of Russia
Email: Volkov-vaa@yandex.ru
Lesnoy, Sverdlovsk region
E Beltyukov
Ural State Medical University Ministry of Health of RussiaEkaterinburg
参考
- Геппе Н.А., Мокина Н.А., Малахова-Капанадзе М.А. Современные возможности применения антилейкотриеновых препаратов в терапии бронхиальной астмы у детей. Рос. Аллергол. Журн. 2007, № 3, прил. 1, с. 9.
- Bisgaard H., Zielen S., Garcia-Garcia M.L. et al. Montelukast reduces asthma exacerbations in 2- to 5-year-old children with intermittent asthma. Amer. J. Respir. Crit. Care Med. 2005, v. 171, р. 315-322.
- Lagos J.A., Marshall G.D. Montelukast in the management of allergic rhinitis. Ther. Clin. Risk. Manag. 2007, v. 3, р. 327-332.
- Phan H., Moeller M.L., Nahata M.C. Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast. Drugs. 2009, v. 69, р. 2541-2576.
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