Hypersensitivity reactions to iodinated contrast media


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Abstract

Hypersensitivity reactions to iodinated contrast media are a pressing public health issue. Lack of understanding of pathogenetic mechanisms of such reactions leads to unjustified refuse of diagnostic and therapeutic procedures using iodinated contrast agents. Reactions of hypersensitivity to other iodine-containing medications are not a contraindication for use of contrast agents. Skin allergy tests are only performed in the patients who had a history of allergic reactions to iodinated contrast media. Usually it is possible to determine an alternative agent by means of skin tests. Premedication before a contrast-enhanced radiological examination has to be indicated to all patients with previous history of allergic disease.

About the authors

L G Khludova

NRC Institute of Immunology FMBA ofRussia

Email: lg.khludova@gmail.com
младший научный сотрудник отделения иммунологии взрослых

T N Myasnikova

NRC Institute of Immunology FMBA ofRussia

кандидат медицинских наук, старший научный сотрудник отделения иммунологии взрослых

V V Smirnov

NRC Institute of Immunology FMBA ofRussia

доцент, кандидат фармацевтических наук, зав. лабораторией клинической фармакологии

T V Latysheva

NRC Institute of Immunology FMBA ofRussia

профессор, доктор медицинских наук, Заслуженный врач РФ, зав. отделением иммунологии взрослых

M R Khaitov

NRC Institute of Immunology FMBA ofRussia

член-корреспондент РАМН, директор

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