Chronic urticaria in theory and practice. Experience of UCARE-centers for clinicians


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Abstract

Chronic urticaria (CU) is an urgent medical and social problem. The instruments of everyday clinical practice are international and domestic guidelines which briefly reflect modern ideas about various aspects of CU. Recently, a new opportunity has emerged to expand theoretical and practical experience in the management of patients with CU, to carry out educational activities to disseminate modern knowledge about urticaria, to conduct research in the field of studying the pathogenesis, treatment, and prevention of exacerbations of the disease. This opportunity is realized through the centers of excellence for working with such patients (GA2LEN UCARE centers). One of the five Russian centers, have prepared and conducted an online training program “Chronic urticaria: scientific and medical achievements and practical aspects of patient management” at the Federal State Budgetary Institution State Research Center “Institute of Immunology” FMBA of Russia. The event was held by the employees of the Federal State Budgetary Institution State Research Center “Institute of Immunology” of the FMBA of Russia on November, 2020.

About the authors

Natalia I. Ilyina

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Author for correspondence.
Email: instimmun@yandex.ru
ORCID iD: 0000-0002-3556-969X
SPIN-code: 6715-5650

MD, Dr. Sci. (Med.), Professor

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Inna V. Danilycheva

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: ivdanilycheva@mail.ru
ORCID iD: 0000-0002-8279-2173
SPIN-code: 4547-3948

MD, Cand. Sci. (Med.)

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Irina V. Dorofeeva

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: idorofeeva1@gmail.com
ORCID iD: 0000-0002-4423-1797

MD

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Olga G. Elisyutina

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: el-olga@yandex.ru
ORCID iD: 0000-0002-4609-2591
SPIN-code: 9567-1894

MD, Dr. Sci. (Med.)

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Oksana M. Kurbacheva

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: kurbacheva@gmail.com
ORCID iD: 0000-0003-3250-0694
SPIN-code: 5698-6436

MD, Dr. Sci. (Med.), Professor

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Elena A. Latysheva

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: ealat@mail.ru
ORCID iD: 0000-0002-1606-205X
SPIN-code: 2063-7973

MD, Dr. Sci. (Med.)

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Loliana S. Litvin

Novartis Pharma LLC

Email: loliana.litvin@novartis.com
ORCID iD: 0000-0002-2229-1078
SPIN-code: 6105-1370

MD, Cand. Sci. (Med.)

Russian Federation, Moscow

Irina A. Manto

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: irina.manto@yandex.ru
ORCID iD: 0000-0001-6432-394X
SPIN-code: 7944-5159

MD, Cand. Sci. (Med.)

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Evgeniya V. Nazarova

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: evallergo@yandex.ru
ORCID iD: 0000-0003-0380-6205
SPIN-code: 4788-7407

MD, Cand. Sci. (Med.)

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Ksenia S. Pavlova

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: ksenimedical@gmail.com
ORCID iD: 0000-0002-4164-4094
SPIN-code: 7593-0838

MD, Cand. Sci. (Med.)

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Anastasia S. Primak

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: soulcreek.94@mail.ru
ORCID iD: 0000-0003-1309-5101

MD

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Elena S. Fedenko

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: efedks@gmail.com
ORCID iD: 0000-0003-3358-5087
SPIN-code: 5012-7242

MD, Dr. Sci. (Med.), Professor

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

Rosalia V. Schubelko

National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia

Email: spapharia@gmail.com
ORCID iD: 0000-0001-6993-9831
SPIN-code: 4553-3234

MD, Cand. Sci. (Med.)

Russian Federation, 24, Kashirskoye shosse, Moscow, 115522

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 2. International Urticaria Day Announcement. (https://urticariaday.org/urticaria-day-2020/urticaria/).

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3. Fig.1. Information for patients with urticaria about the upcoming International Urticaria Day educational event.

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4. Fig. 3. Studied mechanisms of mast cell and basophil activation in CSU (adapted from [12]).

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5. Fig. 4. Determination of urticaria symptom control (UCT-test) [29].

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6. Fig. 5. Algorithm for drug treatment of patients with chronic urticaria [4].

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