Oral food challenges in clinical practice: a missing element of food allergy diagnosis in Russia
- Authors: Levina D.M.1, Korsunskiy I.A.1, Munblit D.B.2
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Affiliations:
- The Speranskiy Children’s Hospital
- Imperial College London
- Issue: Vol 17, No 4 (2020)
- Pages: 19-29
- Section: Reviews
- URL: https://journals.rcsi.science/raj/article/view/121532
- DOI: https://doi.org/10.36691/RJA1391
- ID: 121532
Cite item
Abstract
Food allergy is one of the most prevalent allergic conditions, causing reduction in patient quality of life. It is linked with high levels of anxiety due to potential life-threatening reactions, and high economic burden for a healthcare system. Food allergy affects approximately 5 to 10% of children around the world. In Russian Federation the diagnosis of food allergy is primarily based on clinical history, laboratory test results, examination and elimination of suspected food. Meanwhile oral food challenge (OFC) is considered a “gold standard” of food allergy diagnosis by most of professional bodies nationally and internationally. OFC is a diagnostic procedure involving administration of a causative allergen in gradually increasing amount under a close medical supervision. The method is safe, highly specific and sensitive and is widely used around the world for more than 45 years. The main goals of OFC include food allergy diagnosis and presence of tolerance evaluation, which may result in diet expansion. OFC may also help establishing both, reaction severity and dose needed to elicit reaction, which may further assist with alleviation of patients’ anxiety. In this paper we discuss existing approaches to the diagnosis of food allergy in Russian Federation and review available recommendations on OFC outlined in international guidelines.
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##article.viewOnOriginalSite##About the authors
Daria M. Levina
The Speranskiy Children’s Hospital
Email: LevinaDasha95@mail.ru
ORCID iD: 0000-0001-6322-7294
SPIN-code: 8112-4185
MD, Specialist Trainee in Pediatrics
Russian Federation, MoscowIlya A. Korsunskiy
The Speranskiy Children’s Hospital
Email: iliakors@gmail.com
Head of Allergy and Immunology Department, MD, PhD
Russian Federation, MoscowDaniel B. Munblit
Imperial College London
Author for correspondence.
Email: daniel.munblit08@imperial.ac.uk
ORCID iD: 0000-0001-9652-6856
Honorary Senior Lecturer. Inflammation, Repair and Development Section, National Heart & Lung Institute
United Kingdom, St. Mary`s Campus, Wright Fleming Building, Norfolk Place, Paddington, W2 1PGReferences
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