Serum periostin level in children of preschool age with recurrent wheezing episodes and in healthy children: a cross-sectional study
- Authors: Shakhova NV1, Kamaltynova EM2, Kolesnikova OI1, Kashinskaya TS1
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Affiliations:
- Altai State Medical University
- Siberian State Medical University
- Issue: Vol 16, No 2 (2019)
- Pages: 45-49
- Section: Articles
- URL: https://journals.rcsi.science/raj/article/view/121458
- DOI: https://doi.org/10.36691/RJA1197
- ID: 121458
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Abstract
Background. The level of serum periostin in preschool children with recurrent wheezing episodes has been studied. Objective. To determine the serum periostin level in preschool children with recurrent wheezing episodes, compared to healthy children. Results. 101 children of 3-4 years old took part in the study, 72 of them had recurrent wheezing episodes (more than 3 episodes over the past year) and 29 - healthy individuals. Statistically significant differences in serum periostin level between children with recurrent wheezing episodes and healthy children were not found. The level of serum periostin (median, quartile) is 3.0 (1.8; 4.0) ng/ml in children with recurrent wheezing episodes and 2.7 (1.7; 3.6) ng/ml in healthy children (p=0.296). The area under the ROC curve (AUC) was 0.56 (95% CI 041-0.68). Conclusion. The level of serum periostin in children with recurrent wheezing episodes does not differ from the level in healthy children.
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##article.viewOnOriginalSite##About the authors
N V Shakhova
Altai State Medical University
Email: natalia.shakhova@mail.ru
кандидат медицинских наук, доцент кафедры пропедевтики детских болезней
E M Kamaltynova
Siberian State Medical Universityдоктор медицинских наук, доцент кафедры факультетской педиатрии с курсом детских болезней лечебного факультета
O I Kolesnikova
Altai State Medical Universityдоктор медицинских наук, профессор кафедры педиатрии с курсом ДПО
T S Kashinskaya
Altai State Medical Universityассистент кафедры пропедевтики детских болезней
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