CASE OF A DRESS SYNDROME WITH EOSINOPHILIC PNEUMONIA


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Abstract

The case of the DRESS syndrome developed at the 64 years old patient after carbamazepine intake is reported.
Clinical manifestation of a DRESS syndrome was characterized by a fever, leucocytosis, high eosinophilia of
peripheral blood and sputum, multivisceral involving: skin (maculopapular exanthema), liver (hepatitis), lungs
(eosinophilic pneumonia), lymphadenopathy. Treatment with prednisolone for two months (a starting doze of
60 mg /day) caused full recovery of the patient.

About the authors

I I Vorzheva

ГОУ ДПО Иркутский государственный институт усовершенствования врачей

ГОУ ДПО Иркутский государственный институт усовершенствования врачей

B A Chernyak

ГОУ ДПО Иркутский государственный институт усовершенствования врачей

Email: bores@angara.ru
ГОУ ДПО Иркутский государственный институт усовершенствования врачей

I I Vorzheva

Irkutsk State Institute for Medical Doctors Postgraduate Education

Irkutsk State Institute for Medical Doctors Postgraduate Education

B A Chernyak

Irkutsk State Institute for Medical Doctors Postgraduate Education

Irkutsk State Institute for Medical Doctors Postgraduate Education

References

  1. Bocquet H., Bagot M., Roujeau J.C. Drug-induced pseudolymphoma and drug hypersensitivity syndrome (Drug Rash with Eosinophilia and Systemic Symptoms: DRESS). Semin Cutan Med. Surg. 1996, v. 15, p. 250-257.
  2. Shiohara T., Inaoka M., Kano Y. Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interpla among herpesviruses and antiviral and antidrug immune responses. Allergol. Int. 2006, v. 55, p. 1-8.
  3. Drug hypersensitivity/Editor W. Pichler. Basel: KARGER, 2007, 438 p.
  4. Аллергология и иммунология: национальное руководство. Под ред. Р.М. Хаитова, Н.И. Ильиной. М.,«ГЭОТАР-Медиа». 2009, 656 с.
  5. Walsh S., Creamer D. Drug reaction with eosinophilia and systemic symptoms (DRESS): a clinical update and review of current thinking. Clinical and Experimental Dermatology. 2011, v. 36, Nо. 1, p. 6-11.
  6. Cottin V., Cordier J.F. Eosinophilic pneumonias. Allergy. 2005, v. 60, Nо. 7, p. 841-857.
  7. Воржева И.И. DRESS-синдром как одна из тяжелых форм лекарственной гиперчувствительности. Доктор Ру. 2010, № 2, с. 32-36.
  8. Horsfield P., Deshpande S., Ellis R. Killing with kindness? Drug reaction eosinophilia with systemic symptoms (DRESS) masquerading as acute severe sepsis. J. Antimicrob. Chem. 2009, v. 64, Nо. 6, р. 663-665.

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