Allergological and immunological parameters and effectiveness of treatment of timely and later diagnosed bronchial asthma in children

Relevance. Timely diagnostics of bronchial asthma and the prescription of adequate therapy in children is an important problem at the present time. Purpose. To conduct a comparative analysis of clinical, immunological parameters, results of allergological examination and to evaluate the effectiveness of basic therapy in timely and late diagnosed bronchial asthma (BA) in children. Materials and methods. 155 children aged 5-15 years old with timely and late diagnosed mild persistent BA were under the observation. Modern immunological, allergological, functional diagnostic methods were used. Results. It was proved that late diagnosis of the disease is characterized by polysensitization and significant immunological disorders. It was shown that timely prescription of anti-inflammatory basic therapy with inhaled glucocorticosteroid budesonid in BA children leads to a complete control of BA resulting in recovery of the lung function parameters; in late diagnostics more prolonged courses of treatment are required.

bronchial asthma, children, allergy, late diagnosis, immunological features, anti-inflammatory therapy, inhaled corticosteroids, lung function