Anomalies of the Constitution and Tuberculosis Infection in Children
- Authors: Yarovaya I.A1, Lozovskaya M.E1, Vasilieva E.B1, Klochkova L.V1, Noskova O.M2, Bikova I.A2
-
Affiliations:
- St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
- Saint Petersburg State Healthcare Institution “Children’s City Infectious Diseases Hospital No 3”
- Issue: Vol 8, No 3 (2017)
- Pages: 62-68
- Section: Articles
- URL: https://journals.rcsi.science/pediatr/article/view/6699
- DOI: https://doi.org/10.17816/PED8362-68
- ID: 6699
Cite item
Full Text
Abstract
Phenotypical implications of genetic features are anomalies of the constitution or diathesis. A research objective children had an identification with a tuberculosis infection of occurrence of diathesis. 222 children aged from 1 year up to 14 years are examined: 106 children with active forms of tuberculosis; 54 children with residual post-tubercular changes; 62 children infected with MBT. Limfatiko-hypoplastic, allergic, neuroarthritic, exudative and catarral diathesis was taped. Children with limfatiko-hypoplastic (17.0 ± 3.7%) and neuroarthritic diathesis most often occur among patients with active tuberculosis (17.0 ± 3.7%), children with allergic diathesis are more rare (10.4 ± 3.0% of cases. The least favorable current of active forms of tuberculosis became perceptible at children with limfatiko-hypoplastic diathesis: the complicated forms of tuberculosis became perceptible at them in 27.8 ± 10.6% of cases. At patients with neuroarthritic diathesis the complicated forms developed less often - in 11.1 ± 7.4% of cases. Children with allergic diathesis transferred only uncomplicated forms of primary period of tuberculosis. At children without anomalies of the constitution the complicated current was observed often - in 27.6 ± 5.9% of cases. Frequency of occurrence of children with allergic diathesis is higher at patients with residual post-tubercular changes (29.6 ± 6.2%) and the infected MBT (33.8 ± 6.1%), than at patients with active tuberculosis (10.4 ± 3.0%). Existence of a certain anomaly of the constitution in many respects predetermines the course of a tuberculosis infection.
Full Text
##article.viewOnOriginalSite##About the authors
Iulia A Yarovaya
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: julia_yarovaya@mail.ru
MD, PhD, Associate Professor, Department of TB
Russian Federation, Saint Petersburg, RussiaMarina E Lozovskaya
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: lozovskaja-marina@rumbler.ru
MD, PhD, Dr Med Sci, Professor, Head, Department of TB
Russian Federation, Saint Petersburg, RussiaElena B Vasilieva
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: helenchern27@mail.ru
MD, PhD, Associate Professor, Department of TB
Russian Federation, Saint Petersburg, RussiaLudmila V Klochkova
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: lklochkova@yahoo.com
MD, PhD, Associate Professor, Department of TB
Russian Federation, Saint Petersburg, RussiaOlga M Noskova
Saint Petersburg State Healthcare Institution “Children’s City Infectious Diseases Hospital No 3”
Email: julia_yarovaya@mail.ru
Tuberculosis Department
Russian Federation, Saint Petersburg, RussiaIrina A Bikova
Saint Petersburg State Healthcare Institution “Children’s City Infectious Diseases Hospital No 3”
Email: egorovairina88@mail.ru
Tuberculosis Department
Russian Federation, Saint Petersburg, RussiaReferences
- Баженова Л.К., Исаева Л.А., Карташева В.И. Детские болезни: учебник для студентов вузов (под ред. Исаевой Л.А.). – 3-е изд., испр. – М.: Медицина, 1994. – С. 157–167. [Bazhenova LK, Isaeva LA, Kartasheva VI. Detskie bolezni: uchebnik dlya studentov vuzov (Ed by L.A. Isaevoj). Moscow: Meditcina; 1994. P. 157-167. (In Russ.)]
- Васильева Е.Б., Клочкова Л.В. Клинико-эпидемиологическая характеристика туберкулеза у детей раннего возраста // Педиатр. – 2010. – Т. 1. – № 1. – C. 17. [Vasil’eva EB, Klochkova LV. Klinoko-epidemologicheskaya charakteristika tuberkuleza u detej rannego vozrasta. Pediatr. 2010:1(1):17. (In Russ.)]
- Вельтищев Е.Ю. Наследственное предрасположение к болезням, диатезам и пограничным состояниям у детей // Педиатрия. – 1984. – № 12. – С. 3–9. [Vel’tishchev EYu. Nasledstvennoe predraspolozhenie k boleznyam, diatezam i pogranichnym sostoyaniyam u detej. Pediatriya. 1984;(12):3-9. (In Russ.)].
- Детские болезни: учебник / Под ред. А.А. Баранова. – 2-е изд. – М.: ГЭОТАР-Mедиа, 2009. – C. 47–60. [Detskie bolezni: uchebnik. Ed by A.A. Baranova. 2nd ed. Moscow: GEHOTAR-Media; 2009. P. 47-60. (In Russ.)]
- Маслов М.С. Учение о конституциях и аномалиях конституции в детском возрасте. Клинические лекции для врачей и студентов в монографическом изложении. — 3-е изд., доп., – Л.: Медгиз, 1926. [Maslov MS. Uchenie o konstituciyah i anomaliyah konstitucii v detskom vozraste. Klinicheskie lekcii dlya vrachej i studentov v monograficheskom izlozhenii. 3th ed. Leningrad: Medgiz; 1926. (In Russ.)]
- Маслов М.С. Лекции по факультетской педиатрии. – Л.: Медгиз, 1960. [Maslov MS. Lekcii po fakul’tetskoj pediatrii. Leningrad; Medgiz; 1960. (In Russ.)]
- Носкова О.М., Лозовская М.Э., Король О.И., и др. Методы выявления и характеристика клинических проявлений туберкулезной инфекции у детей и подростков // Проблемы туберкулеза. – 1995. – № 5. – C. 22. [Noskova OM, Lozovskaya ME, Korol’ OI, et al. Metody vyyavleniya i harakteristika klinicheskih proyavlenij tuberkuleznoj infekcii u detej i podrostkov. Problemy tuberkuloza. 1995;(5):22. (In Russ.)].
- Туберкулез у детей и подростков: руководство / Под редакцией О.И. Король, М.Э. Лозовской. – СПб.: ПИТЕР. – 2005. – 424 с. [Tuberkulez u detej i podrostkov. Rukovodstvo Ed by O.I. Korol’, M.E. Lozovskoj. Saint Petersburg; PITER; 2005. (In Russ.)]
- Шабалов Н.П. Детские болезни: учебник. СПб.: ПИТЕР, 1999. – С. 89–109. [Shabalov NP. Detskie bolezni. Uchebnik. Saint Petersburg: PITER; 1999. P. 89-109. (In Russ.)]