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Post a Comment Lesion of the mucous membrane of the stomach, caused by chlamydia in children with chronic glomerulonephritis
- Authors: Chikulaeva E.V1, Melnikova V.F1, Nasyrov R.A1
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Affiliations:
- St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
- Issue: Vol 8, No 3 (2017)
- Pages: 51-56
- Section: Articles
- URL: https://journals.rcsi.science/pediatr/article/view/6697
- DOI: https://doi.org/10.17816/PED8351-56
- ID: 6697
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Abstract
We studied biopsies of gastric mucosa and the gastric antrum bodies obtained from 60 children with chronic gastritis and chronic gastritis in combination with chronic glomerulonephritis. Clinical data of patients (age, gender, duration of the underlying disease, conducted therapy, the results of laboratory and instrumental studies) were studied. It conducts research using histological and immunohistochemical methods. A morphological study of the sections found gastrobiopsies characteristic manifestations of chronic gastritis c signs of chlamydial lesions. The immunohistochemical method determined Chlamidia trachomatis antigens in the antrum and corpus. The positive expression in the epithelial cells of glands and endothelial microvascular gastric mucosa with concomitant lesions of the stomach and kidneys. The possibility of the development of chronic gastritis chlamydial infection in chronic glomerulonephritis. Based on the obtained results was made comprehensive assessment of the gastric mucosa based on morphological, immunohistochemical and clinical data. The features of stromal-vascular responses in the development of chronic gastritis occurring in isolation and combined with chronic glomerulonephritis. The effect of steroid therapy, as a cause of decrease in protective mechanisms of gastric mucosa in children. The data supporting the need for immunohistochemical studies for the etiologic diagnosis of chronic gastritis and the subsequent selection of appropriate therapy.
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##article.viewOnOriginalSite##About the authors
Elena V Chikulaeva
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: elena_chikulaeva@mail.ru
Department of Pathological Anatomy at the Rate of Forensic Medicine
Russian Federation, Saint Petersburg, RussiaValentina F Melnikova
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: melnikova.val@yandex.ru
MD, PhD, Dr Med Sci Professor. Department of Pathological Anatomy at the Rate of Forensic Medicine
Russian Federation, Saint Petersburg, RussiaRuslan A Nasyrov
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: ran.53@mail.ru
MD, PhD, Dr Med Sci Professor Head. Department of Pathological Anatomy at the Rate of Forensic Medicine
Russian Federation, Saint Petersburg, RussiaReferences
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