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发表评论 Giant hepatic hemangiomas in newborns, review literature. Two cases of giant congenital hepatic hemangiomas
- 作者: Podkamenev A.V.1, Syrtsova A.R.1, Ti R.A.1, Kuzminykh S.V.1, Kondratiev G.V.1, Myznikova I.V.1, Kostylev A.A.2
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隶属关系:
- St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
- St. Petersburg’s Children’s City Multidisciplinary Clinical Specialized Center of High Medical Technologies
- 期: 卷 11, 编号 5 (2020)
- 页面: 57-65
- 栏目: Clinical observation
- URL: https://journals.rcsi.science/pediatr/article/view/62351
- DOI: https://doi.org/10.17816/PED11557-65
- ID: 62351
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详细
Hemangiomas are the most frequent tumors of childhood age. In the first year of life their prevalence is 10–12%. Among premature children, the prevalence of hemangiomas correlates with the degree of prematurity. Liver hemangiomas are a wide range of benign vascular formations that can acquire both malignant course and capable of spontaneous regression. Small-sized hemangiomas generally do not require specific treatment and proceed asymptomally. Large-sized formations can cause life-threatening conditions such as severe thrombocytopenia with coagulopathy (Kazabah–Merrit syndrome), anaemia, tumor hemorrhage, spontaneous and traumatic tumor breaks, heart failure associated with intra-tumor bypass of blood flow, abdominal compression syndrome, severe hypothyroidism. Diagnosis of this pathology is carried out on the basis of a set of data of medical imaging, laboratory diagnostics and clinical picture. This review presents key points of general classification, the most characteristic diagnostic signs, as well as basic algorithms of treatment of liver hemangiomas in newborns and children of the first year of life. There are also described 2 clinical cases of newborns with giant liver hemangiomas, which were examined and treated in the pathology department of newborns and infants of Perinatal Center of St. Petersburg State Pediatric Medical University with a description of the peculiarities of the course of each of them.
作者简介
Alexey Podkamenev
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
编辑信件的主要联系方式.
Email: podkamenev@hotmail.com
MD, PhD, Dr. Sci. (Med.), Associate Professor, Department of Surgical Diseases of Childhood
俄罗斯联邦, Saint PetersburgArina Syrtsova
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: syrcovaarina@gmail.com
Pediatric Surgeon, Operating Department, Perinatal Center
俄罗斯联邦, Saint PetersburgRoman Ti
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: sprut009@yandex.ru
Pediatric Surgeon, Operating Department, Perinatal center
俄罗斯联邦, Saint PetersburgSvetlana Kuzminykh
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: svkuzminykh@yandex.ru
Pediatric Surgeon, Operating Department, Perinatal center
俄罗斯联邦, Saint PetersburgGleb Kondratiev
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: spbgvk@mail.ru
Pediatric Oncologist, Assistant Professor, Department of With a Course of Radiation Oncology Diagnostics and Radiotherapy
俄罗斯联邦, Saint PetersburgIrina Myznikova
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: irinayurko2014@yandex.ru
Neonatologist, Head of the Department of Pathology of Newborns and Infants, Perinatal center
俄罗斯联邦, Saint PetersburgAlexandr Kostylev
St. Petersburg’s Children’s City Multidisciplinary Clinical Specialized Center of High Medical Technologies
Email: aka181091@gmail.com
Pediatric Oncologist, Pediatric Oncologist, Department of Oncohematology
俄罗斯联邦, Saint Petersburg参考
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