Non-traditional methods of microbiota disorders correction in children born by cesarean section
- Authors: Barinova V.V.1, Bushtyreva I.O.1, Ivanov D.O.2, Kuznetsova N.B.3, Artouz E.E.3
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Affiliations:
- Clinic of Professor Bushtyreva
- Saint Petersburg State Pediatric Medical University
- Rostov State Medical University
- Issue: Vol 15, No 1 (2024)
- Pages: 79-89
- Section: Reviews
- URL: https://journals.rcsi.science/pediatr/article/view/263099
- DOI: https://doi.org/10.17816/PED15179-89
- ID: 263099
Cite item
Abstract
The high frequency of cesarean sections, associated with an increase in the number of complications of this surgery, worries not only obstetricians and gynecologists around the world, but also pediatricians. Excessive medicalization of such a biologically natural process as childbirth, an increase in the frequency of caesarean section, the lack of contact of the fetus with the microflora of the mother’s vagina, subsequent difficulties in establishing breastfeeding directly affect the formation of the intestinal microbiota of a child in the first year of life. Today, the gut microbiome is considered as a separate human organ that determines the predisposition to the development of obesity, diabetes mellitus, insulin resistance, allergies, autism and even depression. By correcting the intestinal microbiota of a child of the first year of life, it is possible to influence the risks of the formation of these diseases. The simplest and most physiological way is to establish long-term breastfeeding, since it is the oligosaccharides of the breast milk that increase the level of Bifidobacteria. Probiotic correction also seems promising. The review presents new technologies for restoring the intestinal microbiota of children born by caesarean section, who, for objective reasons, avoided contact with the mother’s vaginal microflora. Some of these technologies are quite controversial, some of them, such as vaginal seeding, seem easy to implement and promising. Their further study on large cohorts of patients will make it possible to fully assess their safety and effectiveness in the prevention of microbiome disorders in children of the first year of life.
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##article.viewOnOriginalSite##About the authors
Victoria V. Barinova
Clinic of Professor Bushtyreva
Author for correspondence.
Email: victoria-barinova@yandex.ru
ORCID iD: 0000-0002-8584-7096
SPIN-code: 5068-0680
Scopus Author ID: 2578513
ResearcherId: AAH-3314-2019
PhD, MD, obstetrician-gynecologist, Deputy Director for Development
Russian Federation, 58/7, Sobornyi lane, 344000, Rostov-on-DonIrina O. Bushtyreva
Clinic of Professor Bushtyreva
Email: kio4@mail.ru
ORCID iD: 0000-0001-9296-2271
SPIN-code: 5009-1565
MD, PhD, Dr. Sci. (Medicine), Professor
Russian Federation, 58/7, Sobornyi lane, 344000, Rostov-on-DonDmitry O. Ivanov
Saint Petersburg State Pediatric Medical University
Email: doivanov@yandex.ru
ORCID iD: 0000-0002-0060-4168
SPIN-code: 4437-9626
MD, PhD, Dr. Sci. (Medicine), Professor, Chief Freelance Neonatologist of the Ministry of Health of Russia, Rector, Head of the Department of Neonatology with courses of Neurology and Obstetrics and Gynecology of the Postgraduate and Additional Professional Education
Russian Federation, Saint PetersburgNatalia B. Kuznetsova
Rostov State Medical University
Email: lauranb@inbox.ru
ORCID iD: 0000-0002-0342-8745
SPIN-code: 1804-5398
MD, PhD, Dr. Sci. (Medicine), Professor of the Simulation Training Center
Russian Federation, Rostov-on-DonEkaterina E. Artouz
Rostov State Medical University
Email: artouz-ekaterina@rambler.ru
5th year Student of the Faculty of Preventive Medicine
Russian Federation, Rostov-on-DonReferences
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