The results of efferent therapy by woman with HIV infection, with amniotic fluid outflow at 23 weeks with growth retardation syndrome of 2 fetus

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Abstract

In the article presents data on the management of a 48-year-old patient with HIV infection, urogenital infection with pregnancy, which occurred as a result of IVF, with premature effusion of amniotic fluid at 23 weeks of pregnancy with the syndrome of growth retardation of 2 fetus in monochoric diamniotic twins. After the discharge of the amniotic fluid, the patient was treated for six days in an infectious hospital, then transferred to the perinatal center, where blood tests noted moderatemanifestations of endotoxicosis, increased levels of aminotransferases and an inflammatory reaction of the body. The course of treatment included detoxification methods (plasmapheresis, hemosorption, photomodification of blood with ultraviolet, laser rays), which contributed to the normalization of blood tests, prolongation of pregnancy for another three weeks in the absence of septic complications after operative childbirth in the mother and in newborn girls. At birth, 1 child’s weight, body length and Apgar score were 750 g., 29 sm. and 3/5 points, respectively, in 2 children – 590 g., 30 sm. and 1/3 points, respectively. The children required treatment from resuscitators, at the second stage of nursing, from rehabilitation specialists.

About the authors

Vladimir V. Vetrov

St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation

Author for correspondence.
Email: vetrovplasma@mail.ru

MD, PhD, Dr Med Sci, Head of Cabinet of Extracorporeal Therapies of Perinatal Center

Russian Federation, Saint Petersburg

Dmitry O. Ivanov

St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation

Email: Radiology@mail.ru

MD, PhD, Dr Med Sci, Professor, Rector

Russian Federation, Saint Petersburg

Vitaly A. Reznik

St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation

Email: vitaliy-reznik@mail.ru

MD, PhD, Associate Professor, Head Physician on Obstetrics and Gynecology

Russian Federation, Saint Petersburg

Larisa A. Romanova

St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation

Email: l_romanova2011@mail.ru

Head, Department of Pregnancy Pathology of the Perinatal Center

Russian Federation, Saint Petersburg

Tat’yana V. Melashenko

St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation

Email: melashenkotat@mail.ru

MD, PhD, Neurologist, Anesthesiology and Intensive Care Neonatal Perinatal Center, Ultrasonic Diagnostic Doctor of Radiation Diagnostics Department No. 2

Russian Federation, Saint Petersburg

Ksenia A. Shandrenko

St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation

Email: kshand@mail.ru

Clinical Intern, Department of Obstetrics & Gynecology

Russian Federation, Saint Petersburg

Tatiana A. Krivolesova

St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation

Email: krivolesova.ta@mail.ru

Head, Сlinical-Diagnostic Department of Perinatal Center

Russian Federation, Saint Petersburg

References

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  2. Стрижаков А.Н., Тимохина Е.В., Игнатко И.В., Белоцерковцева А.Д. Патофизиология плода и плаценты. – М., 2015. – 176 с. [Strizhakov AN, Timokhina EV, Ignatko IV, Belotserkovtseva AD. Patofiziologiya ploda i platsenty. Moscow; 2015. 176 p. (In Russ.)]
  3. Терехина Л.А. Беременность и перинатальные исходы у ВИЧ-инфицированных женщин: Автореф. дис. … канд. мед. наук. – М., 2008. [Terekhina LA. Beremennost’ i perinatal’nye iskhody u VICh-infitsirovannykh zhenshchin. [dissertation] Moscow; 2008. (In Russ.)]
  4. Liem SM, van Baaren GJ, Delemarre FM, et al. Economic analysis of use of pessary to prevent preterm birth in women with multiple pregnancy (ProTWIN trial). Ultrasound Obstet Gynecol. 2014;44(3):338-345. https://doi.org/10.1002/uog.13432.

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2. Fig. 1. Newborn patients E. O. five months after birth

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Copyright (c) 2020 Vetrov V.V., Ivanov D.O., Reznik V.A., Romanova L.A., Melashenko T.V., Shandrenko K.A., Krivolesova T.A.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
 


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