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Post a Comment Endobronchial surfactant administration in full-term newborn with respiratory distress syndrome
- Authors: Ivanov D.O.1, Kiriakov K.S.1, Pshenisnov K.V.1, Tesaeva I.A.2, Nasipova M.U.2, Sizaeva E.A.3, Gabisov A.T.1
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Affiliations:
- St. Petersburg State Pediatric Medical University
- Republican Perinatal Center of the Chechen Republic
- St. Nicholas Children’s Hospital
- Issue: Vol 13, No 6 (2022)
- Pages: 107-115
- Section: Clinical observation
- URL: https://journals.rcsi.science/pediatr/article/view/133046
- DOI: https://doi.org/10.17816/PED136107-115
- ID: 133046
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Abstract
Neonatal respiratory distress syndrome is the leading cause of neonatal acute respiratory failure. Despite the successes achieved and the existing international recommendations, in some cases there is a severe course of this disease, which requires a personalized approach to the patient and intensive care measures.
The article presents a case of successful treatment of acute respiratory distress syndrome in a full-term newborn complicated by pulmonary barotrauma using monobronchial administration of exogenous surfactant under X-ray control. In order to assess the course of the disease and the effectiveness of treatment, a retrospective analysis of medical documentation was carried out. From the first minutes of life, the child had respiratory disorders, which was the basis for non-invasive mechanical lung ventilation — nCPAP (nasal continuous positive airway pressure). Progression of hypercapnia and hypoxemia was revealed over time, and therefore tracheal intubation was performed and convective mechanical ventilation was started with FiO2 = 1,0. Monobronchial administration of exogenous surfactant was a key element of the therapy that allowed to achieve stabilization of the condition and regression of gas exchange disorders with complete recovery of the patient.
Monobronchial administration of surfactant in acute respiratory distress syndrome with heterogeneous lung involvement is an effective treatment option and can be used in clinical practice for refractory hypoxemia.
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##article.viewOnOriginalSite##About the authors
Dmitriy O. Ivanov
St. Petersburg State Pediatric Medical University
Email: doivanov@yandex.ru
MD, PhD, Dr. Sci. (Med.), Professor, Head, Neonatology with Сourses Neurology, Obstetrics and Gynecology Dept, Faculty of Postgraduate Education, Rector
Russian Federation, Saint PetersburgKirill S. Kiriakov
St. Petersburg State Pediatric Medical University
Email: kiryakov.ks@yandex.ru
Anesthesiologist-Resuscitator, Anesthesiology-Resuscitation for Children with Cardiac Surgical Pathology Department, Clinic Hospital
Russian Federation, Saint PetersburgKonstantin V. Pshenisnov
St. Petersburg State Pediatric Medical University
Author for correspondence.
Email: Psh_k@mail.ru
MD, PhD, Dr. Sci. (Med.), Assistant Professor, Professor of the Anesthesiology, Intensive Care and Emergency Pediatrics Departmen, Postgraduate Education
Russian Federation, Saint PetersburgImani A. Tesaeva
Republican Perinatal Center of the Chechen Republic
Email: dr.tesaeva89@mail.ru
Head of the Neonatal Intensive Care Unit
Russian Federation, Groznyi, Chechen RepublicMilana U. Nasipova
Republican Perinatal Center of the Chechen Republic
Email: milananasipova92@gmail.com
Anesthesiologist and Intensive Care Physician of the Neonatal Intensive Care Unit
Russian Federation, Groznyi, Chechen RepublicElena A. Sizaeva
St. Nicholas Children’s Hospital
Email: Lena.sizaeva@yandex.ru
Anesthesiologist and Intensive Care Physician of the Intensive Care Unit
Russian Federation, Saint PetersburgAzamat T. Gabisov
St. Petersburg State Pediatric Medical University
Email: azamgabisov@mail.ru
Resident, Neonatology with Courses in Neurology and Obstetrics-Gynecology Department, Faculty of Postgraduate Education
Russian Federation, Saint PetersburgReferences
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